Integrative Analysis Reveals Shegan-Mahuang Decoction Modulates Immunometabolism and Inflammatory Response in Asthma [RNA-seq]
RNA-seq (gene expression) · mouse · 20 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Mus musculus (mouse)
- Samples
- 20 samples: 5 × lungA vs 5 × lungB vs 5 × lungC vs 5 × lungDGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
Read the full summary ↓
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE300921_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1282679 and SRA study SRP594885. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 20 samples.
How we read this: 4 replicated groups read from 20 sample titles; they account for 20 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM9072186 lungA1 lungA
- GSM9072187 lungA2 lungA
- GSM9072188 lungA3 lungA
- GSM9072189 lungA4 lungA
- GSM9072190 lungA5 lungA
- GSM9072191 lungB1 lungB
- GSM9072192 lungB2 lungB
- GSM9072193 lungB3 lungB
- GSM9072194 lungB4 lungB
- GSM9072195 lungB5 lungB
- GSM9072196 lungC1 lungC
- GSM9072197 lungC2 lungC
- GSM9072198 lungC3 lungC
- GSM9072199 lungC4 lungC
- GSM9072200 lungC5 lungC
- GSM9072201 lungD1 lungD
- GSM9072202 lungD2 lungD
- GSM9072203 lungD3 lungD
- GSM9072204 lungD4 lungD
- GSM9072205 lungD5 lungD
- GSE289723 Interleukin-4 modulates type I interferon to augment anti-tumour immunity [scRNA-Seq] 36 samples shares modulates, rna-seq
- GSE269580 Deletion of a state-specific PD-1 enhancer modulates exhausted T cell fate and function [RNA-Seq] 16 samples shares modulates, rna-seq
- GSE259215 Top2a Differentially Modulates Promoter Activity in Embryonic Stem Cells via Trim28 Recruitment and PRC2 Displacement [RNA-Seq] 12 samples shares modulates, rna-seq
- GSE273516 PROSER1 Modulates DNA Demethylation through Dual Mechanisms to Prevent Syndromic Developmental Malformations [RNA-seq] 12 samples shares modulates, rna-seq
- GSE277304 Macrophage-Specific Lactate Dehydrogenase Expression Modulates Inflammatory Function In Vitro 18 samples shares modulates
- GSE296034 Vagal neuroimmune axis modulates heart failure by limiting monocyte-derived inflammatory CCRL2 macrophage 15 samples shares modulates
- GSE272353 Genetic context modulates aging and degeneration in the murine retina 201 samples shares modulates
- GSE252135 Lamivudine modulates the expression of neurological impairment-related genes and LINE-1 retrotransposons in brain tissues of a down syndrome mouse model 94 samples shares modulates
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.