Transcriptional Response to Non-Steroidal Anti-Inflammatory Drugs and Tryptophan Supplementation
RNA-seq (gene expression) · mouse · 97 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Mus musculus (mouse)
- Samples
- 97 samples
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- Depression of tryptophan may contribute to adverse effects of naproxenNature communications · 2026
Read the full summary ↓
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE301033_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1283109 and SRA study SRP595600. Searching any of these in the dataset finder brings you back here.
The sample list for this study is not cached yet. Press Load samples and it will be fetched from NCBI.
+ 97 more — browse all 97 samples with per-sample file links →
- GSE262881 A single-cell transcriptomic atlas of all cell types in the entire 5xFAD mouse brain in response to dietary inulin supplementation 24 samples shares supplementation
- GSE261676 Desipramine Induces Anti-inflammatory Dorsal Root Ganglion Transcriptional Signatures in the Murine Spared Nerve Injury Model 16 samples shares anti-inflammatory
- GSE183091 Role of REDD1 in mouse skin response to proinflammatory 12-(O)-tetra-decanoyl-acetate (TPA) and anti-inflammatory glucocorticoid fluocinolone acetonide (FA) 8 samples shares anti-inflammatory
- GSE325273 4-1BBL suppresses the induction of anti-inflammatory responses by regulating the metabolic reprogramming of macrophages 6 samples shares anti-inflammatory
- GSE292341 Single cell RNA sequencing of hippocampus and hypothalamus in AD mice with fructose-induced MetS and DHA and NR supplementation 48 samples shares supplementation
- GSE292533 Elevated brain manganese induces motor disease by up-regulating the kynurenine pathway of tryptophan metabolism 44 samples shares tryptophan
- GSE296095 Benefits of Maternal choline supplementation on aged basal forebrain cholinergic neurons in a mouse model of Down syndrome and Alzheimer’s disease 44 samples shares supplementation
- GSE330442 Impact of Reduced Maternal Tryptophan on the Placenta-Brain Axis 41 samples shares tryptophan
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.