Acute hormonal signaling-induced 3D chromatin loop reorganization controls adipocyte thermogenesis [CUT&Run mouse]
ChIP-seq / ATAC-seq (genome binding and open chromatin) · mouse · 10 samples
- What it is
- ChIP-seq / ATAC-seq (genome binding and open chromatin)Where proteins bind the genome, or which regions are open and active.
- Organism
- Mus musculus (mouse)
- Samples
- 10 samples: 3 × H2A.Z, unstimulated BAs vs 3 × H2A.Z, β3-AR-stimulated BAs vs 2 × IgG, unstimuated BAs vs 2 × IgG, β3-AR-stimulated BAsGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- A conserved hormonal signalling-H2A.Z axis rapidly reorganizes 3D chromatin interactions in adipocyte thermogenesisNature metabolism · 2026
Read the full summary ↓
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE301360_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: Look for peak files (.bed, .narrowPeak) and signal tracks (.bigWig) among the supplementary files; the raw reads are on ENA.
Also filed as BioProject PRJNA1284847 and SRA study SRP596443. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 10 samples.
How we read this: 4 replicated groups read from 10 sample titles; they account for 10 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM9081582 H2A.Z, unstimulated BAs-rep1 H2A.Z, unstimulated BAs
- GSM9081583 H2A.Z, unstimulated BAs-rep2 H2A.Z, unstimulated BAs
- GSM9081584 H2A.Z, unstimulated BAs-rep3 H2A.Z, unstimulated BAs
- GSM9081585 IgG, unstimuated BAs_rep1 IgG, unstimuated BAs
- GSM9081586 IgG, unstimuated BAs_rep3 IgG, unstimuated BAs
- GSM9081587 H2A.Z, β3-AR-stimulated BAs-rep1 H2A.Z, β3-AR-stimulated…
- GSM9081588 H2A.Z, β3-AR-stimulated BAs-rep2 H2A.Z, β3-AR-stimulated…
- GSM9081589 H2A.Z, β3-AR-stimulated BAs-rep3 H2A.Z, β3-AR-stimulated…
- GSM9081590 IgG, β3-AR-stimulated BAs-rep2 IgG, β3-AR-stimulated B…
- GSM9081591 IgG, β3-AR-stimulated BAs-rep3 IgG, β3-AR-stimulated B…
- GSE261412 Acute hormonal signaling-induced 3D chromatin loop reorganization controls adipocyte thermogenesis [ChIP-Seq mouse, H3K27ac, H3K4me3, H2AZ] 24 samples shares cut, signaling-induced, reorganization, thermogenesis, chromatin, adipocyte, hormonal, controls
- GSE304211 H4K16ac contributes to chromatin compartment reorganization during mitotic and meiotic transitions [CUTnTAG] 128 samples shares cut, reorganization, chromatin
- GSE289642 Noncanonical PRC2 chromatin association reveals a key role of EZHIP in intergenerational epigenetic memory transition [ChIP-Seq, Cut & Run] 107 samples shares cut, chromatin
- GSE298418 MeCP2 stabilizes the glucocorticoid system in active chromatin regions [CUT&Tag] 63 samples shares cut, chromatin
- GSE274493 The remodeling of bivalent chromatin is essential for mouse peri-implantation embryogenesis [CUT&Tag] 46 samples shares cut, chromatin
- GSE274875 A mutant ASXL1-EHMT complex contributes to heterochromatin dysfunction in clonal hematopoiesis and chronic monomyelocytic leukemia [Cut & Run] 38 samples shares cut, chromatin
- GSE295964 Transcription factor NFYA directs male meiotic entry by facilitating accessible chromatin at the promoters of genes expressed during meiosis [CUT&RUN] 13 samples shares cut, chromatin
- GSE282802 KMT2D controls cerebellar granule cell differentiation by temporally activating neuronal transcriptional factor genes [CUT&RUN] 10 samples shares cut, controls
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.