Deletion of AT1a (Angiotensin II Type 1a) Receptor or Inhibition of Angiotensinogen Synthesis Attenuates Thoracic Aortopathies in Fibrillin1C1041G/+ Mice
RNA-seq (gene expression) · mouse · 26 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Mus musculus (mouse)
- Samples
- 26 samples: 13 × A vs 8 × D vs 5 × CGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- Deletion of AT1a (Angiotensin II Type 1a) Receptor or Inhibition of Angiotensinogen Synthesis Attenuates Thoracic Aortopathies in Fibrillin1(C1041G/+) MiceArteriosclerosis, thrombosis, and vascular biology · 2021
Read the full summary ↓
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE301765_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1287542 and SRA study SRP599289. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 26 samples.
How we read this: 3 replicated groups read from 26 sample titles; they account for 26 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM9088843 A_01 A
- GSM9088844 A_02 A
- GSM9088845 A_03 A
- GSM9088846 A_04 A
- GSM9088847 A_05 A
- GSM9088848 A_06 A
- GSM9088849 A_07 A
- GSM9088850 A_08 A
- GSM9088851 D_01 D
- GSM9088852 D_02 D
- GSM9088853 D_03 D
- GSM9088854 D_04 D
- GSM9088855 D_05 D
- GSM9088856 D_06 D
- GSM9088857 D_07 D
- GSM9088858 D_08 D
- GSM9088859 A14 A
- GSM9088860 A15 A
- GSM9088861 A18 A
- GSM9088862 A19 A
- GSM9088863 A20 A
- GSM9088864 C8 C
- GSM9088865 C12 C
- GSM9088866 C13 C
- GSM9088867 C16 C
- GSM9088868 C17 C
- GSE338380 Hepatocyte angiotensinogen deletion protects against Western diet-induced adiposity and hepatic steatosis under thermoneutral housing 48 samples shares angiotensinogen, angiotensin
- GSE291082 Hepatocyte-specific Angiotensinogen Deficiency Inhibits Western Diet-induced Liver Steatosis With Suppression of Cell Division in Mice 23 samples shares angiotensinogen, angiotensin
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.