Bulk RNA-seq analysis of WT C57BL/6 mise treated with Control, Choleste-help normal lot, toxic lot, and Puberulic acid
RNA-seq (gene expression) · mouse · 20 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Mus musculus (mouse)
- Samples
- 20 samples: 5 × Control vs 5 × Choleste-Help Normal Lot vs 5 × Choleste-Help Toxic Lot vs 5 × Puberulic AcidGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- The Pathophysiological Mechanism of Beni-koji Choleste-Help or Puberulic Acid-Induced Kidney InjuryKidney international reports · 2026
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE301801_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1286011 and SRA study SRP598287. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 20 samples.
How we read this: 4 replicated groups read from 20 sample titles; they account for 20 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM9089983 Control 1 Control
- GSM9089984 Control 2 Control
- GSM9089985 Control 3 Control
- GSM9089986 Control 4 Control
- GSM9089987 Control 5 Control
- GSM9089988 Choleste-Help Normal Lot 1 Choleste-Help Normal Lot
- GSM9089989 Choleste-Help Normal Lot 2 Choleste-Help Normal Lot
- GSM9089990 Choleste-Help Normal Lot 3 Choleste-Help Normal Lot
- GSM9089991 Choleste-Help Normal Lot 4 Choleste-Help Normal Lot
- GSM9089992 Choleste-Help Normal Lot 5 Choleste-Help Normal Lot
- GSM9089993 Choleste-Help Toxic Lot 1 Choleste-Help Toxic Lot
- GSM9089994 Choleste-Help Toxic Lot 2 Choleste-Help Toxic Lot
- GSM9089995 Choleste-Help Toxic Lot 3 Choleste-Help Toxic Lot
- GSM9089996 Choleste-Help Toxic Lot 4 Choleste-Help Toxic Lot
- GSM9089997 Choleste-Help Toxic Lot 5 Choleste-Help Toxic Lot
- GSM9089998 Puberulic Acid 1 Puberulic Acid
- GSM9089999 Puberulic Acid 2 Puberulic Acid
- GSM9090000 Puberulic Acid 3 Puberulic Acid
- GSM9090001 Puberulic Acid 4 Puberulic Acid
- GSM9090002 Puberulic Acid 5 Puberulic Acid
- GSE226609 Mouse lung tissue RNA-Seq from C57Bl6 wild type and ALOX15 KO mice with and without house dust mite (HDM) exposure. 20 samples shares c57bl, rna-seq
- GSE248297 Liver RNA-seq from male C57Bl/6J on a ketogenic diet 15 samples shares c57bl, rna-seq
- GSE316313 Single-cell RNA sequencing of MC38 subcutaneous allograft tumors in C57BL/6J mice treated with FOLFOX alone or in combination with a composite probiotics 9 samples shares c57bl, treated
- GSE306116 Caspase-3 Control of RNA Splicing and Mitochondrial Dynamics in Microglia during Parkinson’s Disease [RNA-Seq] 12 samples shares rna-seq, control
- GSE342137 Comparison of NK cell transcriptomes between C57BL6 and NOD mouse strains 8 samples shares c57bl
- GSE264105 Plate-based scRNA-seq of plasma-positive microglia and plasma-negative microglia in young mice 1111 samples shares rna-seq
- GSE281685 Transcription factor occupancy is affected by genetic variation in the white adipose tissue of C57BL6/j and 129S1/SvImJ mice [ChIP-seq] 16 samples shares c57bl
- GSE326100 scRNA-seq of mouse cochlea organoid cells 768 samples shares rna-seq
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.