Mouse lung tissue RNA-Seq from C57Bl6 wild type and ALOX15 KO mice with and without house dust mite (HDM) exposure.
RNA-seq (gene expression) · mouse · 20 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Mus musculus (mouse)
- Samples
- 20 samples: 5 × WT-PBS biol vs 5 × WT-HDM biol vs 5 × KO-PBS biol vs 5 × KO-HDM biolGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE226609_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA940799 and SRA study SRP425592. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 20 samples.
How we read this: 4 replicated groups read from 20 sample titles; they account for 20 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM7080204 WT-PBS biol rep 1 WT-PBS biol
- GSM7080205 WT-PBS biol rep 2 WT-PBS biol
- GSM7080206 WT-PBS biol rep 3 WT-PBS biol
- GSM7080207 WT-PBS biol rep 4 WT-PBS biol
- GSM7080208 WT-PBS biol rep 5 WT-PBS biol
- GSM7080209 WT-HDM biol rep 1 WT-HDM biol
- GSM7080210 WT-HDM biol rep 2 WT-HDM biol
- GSM7080211 WT-HDM biol rep 3 WT-HDM biol
- GSM7080212 WT-HDM biol rep 4 WT-HDM biol
- GSM7080213 WT-HDM biol rep 5 WT-HDM biol
- GSM7080214 KO-PBS biol rep 1 KO-PBS biol
- GSM7080215 KO-PBS biol rep 2 KO-PBS biol
- GSM7080216 KO-PBS biol rep 3 KO-PBS biol
- GSM7080217 KO-PBS biol rep 4 KO-PBS biol
- GSM7080218 KO-PBS biol rep 5 KO-PBS biol
- GSM7080219 KO-HDM biol rep 1 KO-HDM biol
- GSM7080220 KO-HDM biol rep 2 KO-HDM biol
- GSM7080221 KO-HDM biol rep 3 KO-HDM biol
- GSM7080222 KO-HDM biol rep 4 KO-HDM biol
- GSM7080223 KO-HDM biol rep 5 KO-HDM biol
- GSE228125 Effect of Hyperoxia Exposure on the Neonatal Lungs of WT C57BL6 and PTAFR KO C57BL6 mice 12 samples shares c57bl6, exposure, lung
- GSE322523 Mouse heart RNA-seq in isoproterenol (ISO) injury model with or without polystyrene nanoplastics co-exposure 18 samples shares exposure, rna-seq, without
- GSE315893 Characterization of Subchronic Lung and Brain Consequences Caused by Mouse-Adapted SARS-CoV-2 and Influenza A Infection of C57BL6 mice 44 samples shares c57bl6, lung
- GSE281686 Transcription factor occupancy is affected by genetic variation in the white adipose tissue of C57BL6/j and 129S1/SvImJ mice [RNA-seq] 24 samples shares c57bl6, rna-seq
- GSE330728 Single-nucleus RNA-seq atlas of 17 ASD-risk mouse lines under early-postnatal fluoxetine or lithium exposure (4-plex On-Chip Multiplexed) 53 samples shares exposure, rna-seq
- GSE325692 Multi-omic analysis reveals brain-blood concordance and persistent neuroimmune reprogramming with stress and toxicant exposure in a mouse model of Gulf War Illness [RNA-Seq] 30 samples shares exposure, rna-seq
- GSE296297 Single-cell gene expression profiles of mice lung tissue under PM2.5 exposure 26 samples shares exposure, lung
- GSE286079 Epicutaneous Staphylococcus aureus exposure triggers lung inflammation via epithelia-intrinsic IL-36R signaling in a murine model of the atopic march 25 samples shares exposure, lung
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.