High-fat diet-derived microbial metabolome induces an inflammatory phenotype in intestinal epithelial cells [organoids]
RNA-seq (gene expression) · mouse · 17 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Mus musculus (mouse)
- Samples
- 17 samples
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE302244_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1289716 and SRA study SRP599917. Searching any of these in the dataset finder brings you back here.
The sample list for this study is not cached yet. Press Load samples and it will be fetched from NCBI.
+ 17 more — browse all 17 samples with per-sample file links →
- GSE283495 Intestinal epithelial cell diversity and function in respect to age, anatomical localization, and microbial exposure - the global transcriptome 29 samples shares intestinal, epithelial, microbial
- GSE269973 Signaling basis of gastric epithelial cell differentiation revealed by human and mouse organoids [RNA-Seq] 32 samples shares epithelial, organoids
- GSE225514 Role of RANKL in mouse intestinal epithelial cells 28 samples shares intestinal, epithelial
- GSE285771 Orai1 in pancreatic ductal cells mediates pancreas-intestinal crosstalk in experimental acute pancreatitis via the secretion of antimicrobial peptide REG3B in pancreatic juice 18 samples shares intestinal, microbial
- GSE282601 Intestinal epithelial cell EphB4 deficiency on high fat diet-induced obesity 16 samples shares intestinal, epithelial
- GSE247149 Type III interferons induce pyroptosis in gut epithelial cells and delay tissue restitution upon acute intestinal injury. 16 samples shares intestinal, epithelial
- GSE237833 Intestinal epithelial cell NCoR deficiency ameliorates obesity and metabolic syndrome 14 samples shares intestinal, epithelial
- GSE278384 Colonic Epithelial-derived FGF1 Protects against Inflammatory Bowel Disease via Driving Intestinal Stem Cells Differentiation toward Goblet Cells 12 samples shares intestinal, epithelial
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.