Plasmacytoid dendritic cells are dispensable or detrimental in murine systemic or respiratory viral infections [RNA-Seq 2]
RNA-seq (gene expression) · mouse · 22 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Mus musculus (mouse)
- Samples
- 22 samples: 9 conditions, mostly in duplicateGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- Plasmacytoid dendritic cells are dispensable or detrimental in murine systemic or respiratory viral infectionsNature immunology · 2025
Read the full summary ↓
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE302271_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1289775 and SRA study SRP599902. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 22 samples.
How we read this: 9 replicated groups read from 22 sample titles; they account for 22 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM9101145 1_100321 1
- GSM9101146 1_250321 1
- GSM9101147 1_260521 1
- GSM9101148 2_100321 2
- GSM9101149 2_250321 2
- GSM9101150 3_160621 3
- GSM9101151 3_250321 3
- GSM9101152 4_100321 4
- GSM9101153 4_160621 4
- GSM9101154 4_260521 4
- GSM9101155 5_100321 5
- GSM9101156 5_260521 5
- GSM9101157 6_250321 6
- GSM9101158 6_260521 6
- GSM9101159 7_160621 7
- GSM9101160 7_250321 7
- GSM9101161 7_260521 7
- GSM9101162 8_100321 8
- GSM9101163 8_250321 8
- GSM9101164 8_260521 8
- GSM9101165 9_160621 9
- GSM9101166 9_260521 9
- GSE302124 Plasmacytoid dendritic cells are dispensable or detrimental in murine systemic or respiratory viral infections [RNA-Seq 1] 18 samples shares plasmacytoid, dispensable, detrimental, respiratory, infections, dendritic, systemic, rna-seq
- GSE252188 Tonic type I interferon signaling optimizes the antiviral function of plasmacytoid dendritic cells [Bulk RNA-seq] 15 samples shares plasmacytoid, dendritic, rna-seq
- GSE264620 Oxidized mitochondrial DNA sensing by plasmacytoid dendritic cells bypasses self-tolerance to trigger Tfh dependent autoantibody production [scRNA-seq] 12 samples shares plasmacytoid, dendritic, rna-seq
- GSE285244 Metabolic Deficiencies Underlie Reduced Plasmacytoid Dendritic Cell IFN-I Production following Viral Infection [RNA-Seq] 12 samples shares plasmacytoid, dendritic, rna-seq
- GSE264619 Oxidized mitochondrial DNA sensing by plasmacytoid dendritic cells bypasses self-tolerance to trigger Tfh dependent autoantibody production [RNA-seq] 9 samples shares plasmacytoid, dendritic, rna-seq
- GSE223673 Nr5a2 is dispensable for ZGA but essential for morula development [RNA-seq] 514 samples shares dispensable, rna-seq
- GSE248654 TAF1, the largest subunit of TFIID, is dispensable for adult hematopoiesis [RNA-Seq] 36 samples shares dispensable, rna-seq
- GSE327228 RNA Terminal Uridylyl-Transferases Are Druggable Vulnerabilities in AML, but are Dispensable for Normal Hematopoiesis [RNA-seq] 27 samples shares dispensable, rna-seq
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.