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The effect of pentafactor (M5) treatment on the transcriptome of keratinocyte cell line HaCaT

GSE302830 Homo sapiens Expression profiling by high throughput sequencing 4 samples Submitted 2026/01/05 Platform GPL34284
Summary
HaCAT cells were treated with pentafactor (M5) to construct a psoriasis cell model, which was used to study the pathogenesis of psoriasis at the in vitro level. This study aimed to explore the genes activated by pentafactor (M5) treatment.
Published in
TYMP upregulation mediated by the hyperactivated IL-17/NF-κB1 axis promotes psoriasis through enhancing aberrant keratinization and neutrophil-mediated inflammation
Wang J, Zhou Z, Chen Y et al. · Biology direct 2026 · PMID 41952181 · doi:10.1186/s13062-026-00734-2
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Also filed as BioProject PRJNA1292235 and SRA study SRP601278. Searching any of these in the dataset finder brings you back here.

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