GEO series
Extragenous ILC2s infiltration into the brain after ischemic stroke
GSE302993
Mus musculus
Expression profiling by high throughput sequencing
23 samples
2025/07/23
GPL24247
Summary
Group 2 innate lymphoid cells (ILC2s) are key players in immune regulation and tissue repair in barrier immunity, but they are rarely seen in the brain. We investigated whether ILC2s in the peripheral circulation during the acute phase could infiltrate the brain parenchyma. We first transfer ILC2s intravenously into the MCAO mice and performed RNA sequencing of ILC2s isolated from the blood and the brain at different time points after MCAO.
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Paper (PMID 40853291) ↗
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