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Transcriptomic analysis of lung adenocarcinomas from KP and KPCic mice

GSE303269 Mus musculus Expression profiling by high throughput sequencing 10 samples 2025/09/11 GPL34290
Summary
The transcriptional repressor Capicua (CIC) is negatively regulated by KRAS/MAPK signaling. To characterize the impact of CIC loss on KrasG12V/Trp53-KO-driven lung adenocarcinomas in mice, the transcriptome of tumors from Kras (+/LSLG12V); Trp53 (lox/lox) [KP] and Kras (+/LSLG12V); Trp53 (lox/lox); Cic (lox/lox) [KPCic] mice are compared.
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NCBI GEO page ↗ Paper (PMID 41219537) ↗ {# Names what the click gives you. "Open in finder" meant nothing to a visitor who arrived from a search engine and has never seen the tool. #} Find more mouse RNA-seq datasets →
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