RNA-Seq analysis of GPR68 on basal and acute ischemia-induced transcriptome changes in mouse brain
RNA-seq (gene expression) · mouse · 22 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Mus musculus (mouse)
- Samples
- 22 samples: 6 conditions, mostly with about 4 replicates eachGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- RNA-Seq analysis of knocking out the neuroprotective proton-sensitive GPR68 on basal and acute ischemia-induced transcriptome changes and signaling in mouse brainFASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2021
Read the full summary ↓
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE303321_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1292761 and SRA study SRP601542. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 22 samples.
How we read this: 6 replicated groups read from 22 sample titles; they account for 22 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM9123401 WT sham 1 WT sham
- GSM9123402 WT sham 2 WT sham
- GSM9123403 WT sham 3 WT sham
- GSM9123404 WT mcao left 1 WT mcao left
- GSM9123405 WT mcao left 2 WT mcao left
- GSM9123406 WT mcao left 3 WT mcao left
- GSM9123407 WT mcao left 4 WT mcao left
- GSM9123408 WT mcao right 1 WT mcao right
- GSM9123409 WT mcao right 2 WT mcao right
- GSM9123410 WT mcao right 3 WT mcao right
- GSM9123411 WT mcao right 4 WT mcao right
- GSM9123412 GPR68-/- sham 1 GPR68-/- sham
- GSM9123413 GPR68-/- sham 2 GPR68-/- sham
- GSM9123414 GPR68-/- sham 3 GPR68-/- sham
- GSM9123415 GPR68-/- left 1 GPR68-/- left
- GSM9123416 GPR68-/- left 2 GPR68-/- left
- GSM9123417 GPR68-/- left 3 GPR68-/- left
- GSM9123418 GPR68-/- left 4 GPR68-/- left
- GSM9123419 GPR68-/- right 1 GPR68-/- right
- GSM9123420 GPR68-/- right 2 GPR68-/- right
- GSM9123421 GPR68-/- right 3 GPR68-/- right
- GSM9123422 GPR68-/- right 4 GPR68-/- right
- GSE311449 Single cell RNA-seq of mouse brain vascular cells with Smart-seq2 method 391 samples shares rna-seq, brain
- GSE326452 Bulk RNA-seq of mouse brain following closed head injury: role of IL-1R1 signaling 200 samples shares rna-seq, brain
- GSE237260 Transcriptome Analysis Reveals Gene Expression Changes in a mouse Model of Hyperoxia-induced acute lung injury 12 samples shares changes, acute
- GSE277487 Single-nucleus RNA-seq of mouse cortex following CCI-induced traumatic brain injury across multiple time points 12 samples shares rna-seq, brain
- GSE319252 Eicosapentaenoic Acid Reprograms Cerebrovascular Metabolism and Impairs Repair after Brain Injury, with Relevance to Chronic Traumatic Encephalopathy [mouse_brain_OnurE_RNA-seq] 12 samples shares rna-seq, brain
- GSE248386 ILC2 regulate a Pi16+ fibroblast progenitor niche in the pancreas (acute pancreatitis scRNA-seq) 10 samples shares rna-seq, acute
- GSE308939 Single-cell RNA-seq reveals the keratinocyte heterogeneity and increased interfollicular basal keratinocytes in wound-induced hair follicle neogenesis 6 samples shares rna-seq, basal
- GSE319614 Bulk RNA-seq transcriptome profiling of hippocampus across 17 autism spectrum disorder mouse models 269 samples shares rna-seq
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.