HFD-induced metabolic syndrome is promoted by JNK7b isoform
RNA-seq (gene expression) · mouse · 12 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Mus musculus (mouse)
- Samples
- 12 samples: 6 conditions, mostly in duplicateGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- Mutually exclusive alternative pre-mRNA splicing promotes adaptive metabolic stress signaling by JNKProceedings of the National Academy of Sciences of the United States of America · 2026
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE303383_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1294980 and SRA study SRP602805. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 12 samples.
How we read this: 6 replicated groups read from 12 sample titles; they account for 12 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM9124859 GFP1_J1 GFP1_J
- GSM9124860 GFP2_J1 GFP2_J
- GSM9124861 CRE1_J1 CRE1_J
- GSM9124862 CRE2_J1 CRE2_J
- GSM9124863 FLPO1_J1 FLPO1_J
- GSM9124864 FLPO2_J1 FLPO2_J
- GSM9124865 GFP1_J2 GFP1_J
- GSM9124866 GFP2_J2 GFP2_J
- GSM9124867 CRE1_J2 CRE1_J
- GSM9124868 CRE2_J2 CRE2_J
- GSM9124869 FLPO1_J2 FLPO1_J
- GSM9124870 FLPO2_J2 FLPO2_J
- GSE302874 HFD-inducued metabolic syndrome is promoted by JNK7b isoform. 69 samples shares jnk7b, promoted, isoform
- GSE277336 HFD-inducued metabolic syndrome is promoted by JNK7b isoform 20 samples shares jnk7b, promoted, isoform
- GSE278155 HFD-inducued metabolic syndrome is promoted by JNK7b isoform [Liver_RNAseq] 16 samples shares jnk7b, promoted, isoform
- GSE297857 HFD-inducued metabolic syndrome is promoted by JNK7b isoform 6 samples shares jnk7b, promoted, isoform
- GSE248964 Isoform Usage as a Distinct Regulatory Layer Driving Nutrient-Responsive Metabolic Adaptation (RNA-seq) 117 samples shares isoform
- GSE282889 Reduction of intestinal RIPK1 ameliorates HFD-induced metabolic disorders in female mice 74 samples shares hfd-induced
- GSE298875 Targeted p63 isoform modulation corrects dominant mutations in AEC syndrome without disrupting epidermal homeostasis 6 samples shares isoform
- GSE297765 Targeted p63 isoform modulation corrects dominant mutations in AEC syndrome without disrupting epidermal homeostasis [RNA-seq Mouse] 6 samples shares isoform
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.