Organoid modeling of lung branching morphogenesis and epithelial lineage specification
RNA-seq (gene expression) · mouse · 56 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Mus musculus (mouse)
- Samples
- 56 samples: 44 distinct titles, 6 of them repeatedGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE303739_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1297448 and SRA study SRP594494. Searching any of these in the dataset finder brings you back here.
How we read this: Read from 56 sample titles: 44 distinct titles with little repetition. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM9067318 LO_day8
- GSM9067319 LO_day11
- GSM9067320 LO_day18
- GSM9067321 LO_day11_DCI
- GSM9067324 down-half (2)
- GSM9067325 down-half-left (7)
- GSM9067326 down-half-right (8)
- GSM9067327 intact(0)
- GSM9067328 left-half (3)
- GSM9067329 right-half (4)
- GSM9067330 up-half (1)
- GSM9067331 up-half-left (5)
- GSM9067332 up-half-right (6)
- GSM9067333 E10.5_Tip
- GSM9067334 E11.5_Tip
- GSM9067335 E12.5_Tip
- GSM9067336 E13.5_Tip
- GSM9067337 organoid_E10.5_11d
- GSM9067338 organoid_E10.5_18d
- GSM9067339 organoid_E10.5_32d
- GSM9067340 organoid_E11.5_11d
- GSM9067341 organoid_E13.5_11d
- GSM9067342 organoid_E13.5_19d
- GSM9067343 organoid_E13.5_30d
- GSM9067345 organoid_E14_11d
- GSM9067347 organoid_E14_24d
- GSM9067349 organoid_E9.5_13d
- GSM9067364 28dpt-Donor-derived
- GSM9067365 28dpt-endogenous
- GSM9084900 Lung organoid d8
- GSM9084901 Lung organoid d11
- GSM9084902 Lung organoid d19
- GSM9477004 2C
- GSM9477005 2C+F10
- GSM9477006 2C+MTG
- GSM9477007 2C+VC
- GSM9477008 ALL
- GSM9477009 ALL_r1
- GSM9477010 ALL_r2
- GSM9477011 ALL-FGF10_r1
+ 16 more — browse all 56 samples with per-sample file links →
- GSE300722 Organoid modeling of lung branching morphogenesis and epithelial lineage specification [RNA-Seq] 40 samples shares morphogenesis, specification, epithelial, branching, organoid, modeling, lineage, lung
- GSE253461 Single-cell transcriptional profiling of wildtype Rosa26(YFP) (Y) and Kras(G12D) p53(-/-) Rosa26-YFP (KPY) lung AT2 epithelial cells, AT2 organoids, and co-cultured mesenchymal cells with temporal resolution 39 samples shares epithelial, organoid, lung
- GSE249931 Temporal single-cell profiling of distinct mesenchymal, epithelial, endothelial, and immune cell lineages in the lung after injury 17 samples shares epithelial, lineage, lung
- GSE273123 Aberrant Transitional Alveolar Epithelial Cells Promote Pathogenic Activation of Lung Fibroblasts in Preclinical Fibrosis Modeling (Bulk RNA-Seq) 16 samples shares epithelial, modeling, lung
- GSE319684 Timecourse of FACS sorted Ly6C+ monocytes, tissue resident alveolar macrophages (trAMs), monocyte derived alveolar macrophages (bmAMs) and epithelial cells from SARS-CoV-2 (maVie16) vs. IAV (PR8) infected mouse lungs 176 samples shares epithelial, lung
- GSE287098 Influenza virus-induced type I interferons disrupt alveolar epithelial repair and tight junction integrity in the developing lung 96 samples shares epithelial, lung
- GSE269973 Signaling basis of gastric epithelial cell differentiation revealed by human and mouse organoids [RNA-Seq] 32 samples shares epithelial, organoid
- GSE215179 Selective requirement of 3D genomic organization for the Mdm1-Il22-Ifng locus regulation in initial Th1 cell lineage specification and differentiation 30 samples shares specification, lineage
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.