GEO series
Organoid modeling of lung branching morphogenesis and epithelial lineage specification [RNA-Seq]
GSE300722
Mus musculus
Expression profiling by high throughput sequencing
40 samples
2026/06/23
GPL34290
Summary
In this study, multi-level branching lung organoids (BLOs) were generated from primary tip epithelial cells. Single-cell RNA sequencing demonstrated that BLOs comprise proximal airway and distal alveolar epithelial cell populations, faithfully modeling the developmental trajectory of distal lung epithelial lineages in vitro.
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