← BioTransfer GEO Dataset Finder
GEO series

CITE-seq analysis of murine subcutaneos PDAC tumor models under pan-KRAS inhibitor and/or anti-PD1 treatment combinations

GSE304231 Mus musculus Expression profiling by high throughput sequencing; Other 9 samples Submitted 2025/08/05 Platform GPL19057
Summary
A multi-omic analysis of CITE-seq of a syngeneic model of PDAC unveils distinct phenotypic correlations of augmented anti-tumor immunity and a substantially reduced immunosuppressive tumor microenvironment (TME). This study presents KRASi and anti-PD1 as a promising drug combination for cancer patients with a multi-layered impact on both tumor cell intrinsic, as well as TME-dependent mechanisms.
This dataset
Download

Direct links to NCBI, no account and no request form: the whole study as GSE304231_RAW.tar, processed values as the series matrix, the supplementary file directory, and per-sample supplementary files for any of the 9 samples. Raw sequencing reads are also available from ENA.

Also filed as BioProject PRJNA1299441 and SRA study SRP605505. Searching any of these in the dataset finder brings you back here.

Samples in this study

The sample list for this study is not cached yet. Press Sort into groups and it will be fetched from NCBI.

+ 9 more — browse all 9 samples with per-sample file links →

Similar datasets

Search all mouse RNA-seq datasets in GEO →

Share this dataset

Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.