HIF1 Counteracts FOXO1/Bim-associated Follicle Atresia in Mouse Ovaries by Promoting Bcl-XL Expression
RNA-seq (gene expression) · mouse · 10 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Mus musculus (mouse)
- Samples
- 10 samples: 6 × Sal vs 4 × NACGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
Read the full summary ↓
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE304305_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1300324 and SRA study SRP605794. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 10 samples.
How we read this: 2 replicated groups read from 10 sample titles; they account for 10 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM9147198 NAC-1 NAC
- GSM9147199 NAC-2 NAC
- GSM9147200 NAC-3 NAC
- GSM9147201 NAC-4 NAC
- GSM9147202 Sal-1 Sal
- GSM9147203 Sal-2 Sal
- GSM9147204 Sal-3 Sal
- GSM9147205 Sal-4 Sal
- GSM9147206 Sal-5 Sal
- GSM9147207 Sal-6 Sal
- GSE335191 HIF1 Counteracts FOXO1/Bim-associated Follicle Atresia in Mouse Ovaries by Promoting Bcl-XL Expression. 8 samples shares foxo1, hif1, bim-associated, counteracts, promoting, follicle, atresia, ovaries
- GSE201806 Harmful algal bloom toxin microcystin-LR interferes with PP1-mediated PI3K/AKT/FOXO1 signaling in granulosa cells to disrupt ovarian follicle maturation and ovulation 15 samples shares foxo1, follicle
- GSE304280 α7nAChR activation reduces inflammation and apoptosis, promoting muscle regeneration through the AKT-FOXO1 pathway. 12 samples shares foxo1, promoting
- GSE278867 GFI1-FOXO1 axis regulate NK cell maturation and function [RNA-seq] 74 samples shares foxo1
- GSE282641 HIF1α Mediates Circadian Regulation of Skeletal Muscle Metabolism and Substrate Preference in Response to Time-of-Day Exercise 64 samples shares hif1
- GSE254438 Hepatic BMAL1 and HIF1a regulate a time-dependent hypoxic response and their absence leads to Hepatopulmonary Syndrome II 39 samples shares hif1
- GSE269318 Cancer-intrinsic Cxcl5 orchestrates global metabolic reprogramming of three dimensional cancers by upregulating Hif1α and Myc expression 31 samples shares hif1
- GSE240404 Upregulated FoxO1 promotes arrhythmogenesis in mice with heart failure and preserved ejection fraction 27 samples shares foxo1
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.