MAIT and other innate-like T cells integrate adaptive immune responses to modulate interval-dependent reactogenicity to mRNA vaccines
RNA-seq (gene expression) · human · 259 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Homo sapiens (human)
- Samples
- 259 samples: 259 samples, each with a distinct title — no replicated groupsGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- MAIT and other innate-like T cells integrate adaptive immune responses to modulate interval-dependent reactogenicity to mRNA vaccinesScience immunology · 2025
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE304585_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1301826 and SRA study SRP607053. Searching any of these in the dataset finder brings you back here.
Any grouping that defines a comparison lives in the sample characteristics, which GEO records separately from the titles.
How we read this: Read from 259 sample titles: 259 distinct titles with little repetition. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM9153268 2231_V1 (tempus)
- GSM9153269 2231_V1+1 (tempus)
- GSM9153270 2231_V2 (tempus)
- GSM9153271 2231_V2+1 (tempus)
- GSM9153272 2255_V1 (tempus)
- GSM9153273 2255_V1+1 (tempus)
- GSM9153274 2255_V2 (tempus)
- GSM9153275 2255_V2+1 (tempus)
- GSM9153276 2269_V1 (tempus)
- GSM9153277 2269_V1+1 (tempus)
- GSM9153278 2269_V2 (tempus)
- GSM9153279 2269_V2+1 (tempus)
- GSM9153280 2436_V1 (tempus)
- GSM9153281 2436_V1+1 (tempus)
- GSM9153282 2436_V2 (tempus)
- GSM9153283 2436_V2+1 (tempus)
- GSM9153284 2532_V1 (tempus)
- GSM9153285 2532_V1+1 (tempus)
- GSM9153286 2532_V2 (tempus)
- GSM9153287 2532_V2+1 (tempus)
- GSM9153288 2689_V2 (tempus)
- GSM9153289 2689_V2+1 (tempus)
- GSM9153290 2699_V2 (tempus)
- GSM9153291 2699_V2+1 (tempus)
- GSM9153292 2794_V1 (tempus)
- GSM9153293 2794_V2+1 (tempus)
- GSM9153294 3871_V1 (tempus)
- GSM9153295 3871_V1+1 (tempus)
- GSM9153296 3871_V2 (tempus)
- GSM9153297 3871_V2+1 (tempus)
- GSM9153298 4213_V1+1 (tempus)
- GSM9153299 4213_V2 (tempus)
- GSM9153300 4213_V2+1 (tempus)
- GSM9153301 5067_V1 (tempus)
- GSM9153302 5067_V1+2 (tempus)
- GSM9153303 5067_V2 (tempus)
- GSM9153304 5067_V2+1 (tempus)
- GSM9153305 5083_V1 (tempus)
- GSM9153306 5083_V1+1 (tempus)
- GSM9153307 5083_V2 (tempus)
+ 219 more — browse all 259 samples with per-sample file links →
- GSE304583 MAIT and other innate-like T cells integrate adaptive immune responses to modulate interval-dependent reactogenicity to mRNA vaccines [tempus] 179 samples shares mait, interval-dependent, reactogenicity, innate-like, integrate, adaptive, modulate, vaccines
- GSE304584 MAIT and other innate-like T cells integrate adaptive immune responses to modulate interval-dependent reactogenicity to mRNA vaccines [MAIT] 80 samples shares mait, interval-dependent, reactogenicity, innate-like, integrate, adaptive, modulate, vaccines
- GSE223075 Next Generation Sequencing facilitates to identify the differential expression genes of sorted conventional CD8+ T cells and MAIT cells 35 samples shares mait
- GSE276378 The MAIT cell response to controlled oral enterotoxigenic E. coli challenge 28 samples shares mait
- GSE224205 Next Generation Sequencing facilitates to identify the differential expression genes of MAIT cells treated by bile acids 24 samples shares mait
- GSE270499 IL-23 tunes inflammatory functions of human MAIT cells 21 samples shares mait
- GSE320009 Synergistic role of riboflavin-auxotrophic Enterococcus for MR1 expression and in-tra-tumoral mucosal associated invariant T (MAIT) cell activation 18 samples shares mait
- GSE261270 Next Generation Sequencing facilitates to identify the differential expression genes of expanded MAIT cells upon the stimulation of 5-OP-RU/MR1 tetramer with/without GCDCA/TCDCA/UDCA 18 samples shares mait
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.