Small activating RNA AW1-51 (CEBPA-51) elicits targeted DNA demethylation to promote gene activation [RNA-seq]
DNA methylation · human · 8 samples
- What it is
- DNA methylationChemical marks on DNA that help switch genes on or off.
- Organism
- Homo sapiens (human)
- Samples
- 8 samples: 2 × A549, NC, vs 2 × A549, AW1-51, vs 2 × K562, NC, vs 2 × K562, AW1-51,Groups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
Read the full summary ↓
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE305099_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: Look for beta-value tables or raw IDAT files among the supplementary files.
Also filed as BioProject PRJNA1304428 and SRA study SRP608039. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 8 samples.
How we read this: 4 replicated groups read from 8 sample titles; they account for 8 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM9162218 A549, NC, rep 1 A549, NC,
- GSM9162219 A549, NC, rep 2 A549, NC,
- GSM9162220 A549, AW1-51, rep 1 A549, AW1-51,
- GSM9162221 A549, AW1-51, rep 2 A549, AW1-51,
- GSM9162222 K562, NC, rep 1 K562, NC,
- GSM9162223 K562, NC, rep 2 K562, NC,
- GSM9162224 K562, AW1-51, rep 1 K562, AW1-51,
- GSM9162225 K562, AW1-51, rep 2 K562, AW1-51,
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Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.