Transcriptional Profile in Allergic Contact Dermatitis to Methylisothiazolinone
RNA-seq (gene expression) · human · 24 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Homo sapiens (human)
- Samples
- 24 samples
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- IL-9 and IL-24 biomarkers in the transcriptional signature of contact dermatitis to methylisothiazolinoneFrontiers in immunology · 2025
Read the full summary ↓
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE305246_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1304914 and SRA study SRP608390. Searching any of these in the dataset finder brings you back here.
The sample list for this study is not cached yet. Press Load samples and it will be fetched from NCBI.
+ 24 more — browse all 24 samples with per-sample file links →
- GSE267929 Single cell RNA-sequencing reveals molecular signatures that distinguish allergic from irritant contact dermatitis 21 samples shares dermatitis, allergic, contact
- GSE282562 Transcriptomic analysis of severe allergic patch test reactions to different allergens (nickel, 2-hydroxyethylmethacrylate, methylisothiazolinone and formaldehyde) 59 samples shares methylisothiazolinone, allergic
- GSE208405 RNA-Seq in peripheral blood samples of atopic dermatitis patients of the TREATgermany registry before and after initiation of systemic therapy with Dupilumab 179 samples shares dermatitis
- GSE330551 Th2-primed innate immune amplification defines a distinct atopic dermatitis endotype 174 samples shares dermatitis
- GSE193816 A model of human asthma exacerbation identifies novel transcriptional programs and pathogenic cell circuits in the lower airway mucosa specific to allergic asthma 21 samples shares allergic
- GSE277961 Tralokinumab treatment of Atopic dermatitis induces a progressive transcriptomic response 154 samples shares dermatitis
- GSE121212 Atopic Dermatitis, Psoriasis and healthy control RNA-seq cohort 147 samples shares dermatitis
- GSE328391 Airway immune signatures of protection and disease progression in recent human tuberculosis household contacts [bulk RNA-seq] 125 samples shares contact
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.