GEO series
Female-specific Cx3cr1-driven regulation of ALS and Alzheimer’s risk genes in tauopathy
GSE305471
Mus musculus
Expression profiling by high throughput sequencing
28 samples
2026/03/09
GPL24247
Summary
By introducing haploinsufficiency of Cx3cr1 in the P301S (PS19) transgenic model of tau pathology, we report remarkable transcriptional changes, including crucial amyotrophic lateral sclerosis and Alzheimer’s disease risk genes, several of which showed co-expression, suggesting gene–gene interactions among these genetic risk factors.
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Paper (PMID 41884646) ↗
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