GEO series
Transciptome profile of liver tissues from CD163KO mice after 8 weeks of Western diet.
GSE305484
Mus musculus
Expression profiling by high throughput sequencing
39 samples
2025/10/01
GPL24247
Summary
Liver macrophages have a high expression of the macrophage-specific scavenger receptor CD163 but during metabolic dysfunction-associated steatohepatitis (MASH) development CD163 undergoes increased shedding and downregulated expression in the liver in humans. Herein, we derived a hepatic-transcriptome based dataset to understand the development of early hepatic steatosis in CD163 knockout mice and their littermate controls.
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Paper (PMID 41234701) ↗
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