Preadipocyte uncoupling protein 1 expression invoked by fibroblast growth factors imprints on post-differentiation white and brown adipocyte function
RNA-seq (gene expression) · mouse · 18 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Mus musculus (mouse)
- Samples
- 18 samples: 18 samples, each with a distinct title — no replicated groupsGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- Preadipocyte Uncoupling Protein 1 Expression Invoked by Fibroblast Growth Factors Imprints on Post-Differentiation White and Brown Adipocyte PhenotypeFASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2025
Read the full summary ↓
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE306159_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1309609 and SRA study SRP610733. Searching any of these in the dataset finder brings you back here.
Any grouping that defines a comparison lives in the sample characteristics, which GEO records separately from the titles.
How we read this: Read from 18 sample titles: 18 distinct titles with little repetition. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM9194234 S1_primary white preadipocytes (iWAT), untreated, repl. 1
- GSM9194235 S2_primary white preadipocytes (iWAT), FGF1, repl. 1
- GSM9194236 S3_primary white preadipocytes (iWAT), FGF2, repl. 1
- GSM9194237 S4_primary white preadipocytes (iWAT), FGF4, repl. 1
- GSM9194238 S5_primary white preadipocytes (iWAT), FGF8, repl. 1
- GSM9194239 S6_primary white preadipocytes (iWAT), FGF9, repl. 1
- GSM9194240 S7_primary white preadipocytes (iWAT), untreated, repl. 2
- GSM9194241 S8_primary white preadipocytes (iWAT), FGF1, repl. 2
- GSM9194242 S9_primary white preadipocytes (iWAT), FGF2, repl. 2
- GSM9194243 S10_primary white preadipocytes (iWAT), FGF4, repl. 2
- GSM9194244 S11_primary white preadipocytes (iWAT), FGF8, repl. 2
- GSM9194245 S12_primary white preadipocytes (iWAT), FGF9, repl. 2
- GSM9194246 S13_primary white preadipocytes (iWAT), untreated, repl. 3
- GSM9194247 S14_primary white preadipocytes (iWAT), FGF1, repl. 3
- GSM9194248 S15_primary white preadipocytes (iWAT), FGF2, repl. 3
- GSM9194249 S16_primary white preadipocytes (iWAT), FGF4, repl. 3
- GSM9194250 S17_primary white preadipocytes (iWAT), FGF8, repl. 3
- GSM9194251 S18_primary white preadipocytes (iWAT), FGF9, repl. 3
- GSE273407 Adipose stem cells are sexually dimorphic cells with dual roles as preadipocytes and resident fibroblasts [FACS_castovary_ASC] 58 samples shares preadipocyte, fibroblast, adipocyte
- GSE273416 Adipose stem cells are sexually dimorphic cells with dual roles as preadipocytes and resident fibroblasts [in vitro_SVF] 29 samples shares preadipocyte, fibroblast, adipocyte
- GSE283700 RNA-sequencing of SVF-derived preadipocytes from inguinal adipose tissue of male mice differentiating under control conditions or treated with CGRP 15 samples shares preadipocyte, adipocyte
- GSE229916 Pericytes and perivascular fibroblasts contribute to central nervous system fibrosis in a region dependent manner 832 samples shares fibroblast
- GSE327470 Temporal Uncoupling of Radial Glial Progenitor Cell Lineage Progression in Self-organizing Organoid System 292 samples shares uncoupling
- GSE327468 Temporal Uncoupling of Radial Glial Progenitor Cell Lineage Progression in Self-organizing Organoid System – MADM-CloneSeq 287 samples shares uncoupling
- GSE274992 Splenic fibroblasts control marginal zone B-cell movement and function via two distinct Notch2-dependent regulatory programs 119 samples shares fibroblast
- GSE278990 Single-cell screens identify ADAM12 as a fibroblast checkpoint impeding anti-tumor immunity 73 samples shares fibroblast
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.