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RNAseq analysis of bone marrow plasma cells from Taciflox/flox and Jchain-CreERT2;Taciflox/flox mice

GSE306258 Mus musculus Expression profiling by high throughput sequencing 8 samples Submitted 2026/06/10 Platform GPL24247
Summary
Durable neutralizing antibodies are essential for vaccine-induced protection and are continuously secreted by bone marrow long-lived plasma cells (LLPCs). The longevity of these cells largely dictates the duration of vaccine-induced immune protection. We perfomred conditional deletion of TACI in PCs to analyze the effect of TACI on bone marow plasma cellls using Jchain-CreERT2;Taciflox/flox mice.
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Direct links to NCBI, no account and no request form: the whole study as GSE306258_RAW.tar, processed values as the series matrix, the supplementary file directory, and per-sample supplementary files for any of the 8 samples. Raw sequencing reads are also available from ENA.

Also filed as BioProject PRJNA1310300 and SRA study SRP612234. Searching any of these in the dataset finder brings you back here.

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