Androgen receptor cell-autonomously regulates luminal cell plasticity and regeneration [scRNA-seq]
Single-cell RNA-seq · mouse · 22 samples
- What it is
- Single-cell RNA-seqGene activity measured in thousands of individual cells, so cell types can be told apart.
- Organism
- Mus musculus (mouse)
- Samples
- 22 samples: 22 samples, each with a distinct title — no replicated groupsGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE306891_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: Single-cell studies usually ship their counts as 10x files (matrix.mtx, barcodes.tsv, features.tsv), an .h5 file, or an .rds / .h5ad object that Seurat or Scanpy can open. Look for those among the supplementary files.
Also filed as BioProject PRJNA1312866 and SRA study SRP614809. Searching any of these in the dataset finder brings you back here.
Any grouping that defines a comparison lives in the sample characteristics, which GEO records separately from the titles.
How we read this: Read from 22 sample titles: 22 distinct titles with little repetition. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM9211913 Tmprss2CreERT2, lsl-EYFP, whole prostate, Tamoxifen 2 weeks, scRNAseq
- GSM9211914 Tmprss2CreERT2, lsl-EYFP, whole prostate, Tamoxifen 2 weeks, Multiplexing
- GSM9211915 Tmprss2CreERT2, lsl-EYFP, Arf/Y, whole prostate, Tamoxifen 2 weeks, scRNAseq
- GSM9211916 Tmprss2CreERT2, lsl-EYFP, Arf/Y, whole prostate, Tamoxifen 2 weeks, Multiplexing
- GSM9211917 Tmprss2CreERT2, lsl-EYFP, Arf/Y, whole prostate, Tamoxifen 2 weeks, castrate 2 weeks, RNAseq
- GSM9211918 Tmprss2CreERT2, lsl-EYFP, Arf/Y, whole prostate, Tamoxifen 2 weeks, castrate 2 weeks, Multiplexing
- GSM9211919 Tmprss2CreERT2, lsl-EYFP, Arf/Y, whole prostate, Tamoxifen 2 weeks, castrate 5 days, RNAseq
- GSM9211920 Tmprss2CreERT2, lsl-EYFP, Arf/Y, whole prostate, Tamoxifen 2 weeks, castrate 5 days, Multiplexing
- GSM9211921 Tmprss2CreERT2, lsl-EYFP, Arf/Y, whole prostate, Tamoxifen 2 weeks, castrate 2 weeks, DHT 2 days, RNAseq
- GSM9211922 Tmprss2CreERT2, lsl-EYFP, Arf/Y, whole prostate, Tamoxifen 2 weeks, castrate 2 weeks, DHT 2 days, Multiplexing
- GSM9211923 Tmprss2CreERT2, lsl-EYFP, Arf/Y, whole prostate, Tamoxifen 2 weeks, castrate 2 weeks, DHT 2 weeks, RNAseq
- GSM9211924 Tmprss2CreERT2, lsl-EYFP, Arf/Y, whole prostate, Tamoxifen 2 weeks, castrate 2 weeks, DHT 2 weeks, Multiplexing
- GSM9211925 Tmprss2CreERT2, lsl-EYFP, whole prostate, Tamoxifen 2 weeks, castrate 2 weeks, scRNAseq
- GSM9211926 Tmprss2CreERT2, lsl-EYFP, whole prostate, Tamoxifen 2 weeks, castrate 2 weeks, Multiplexing
- GSM9211927 Tmprss2CreERT2, lsl-EYFP, whole prostate, Tamoxifen 2 weeks, castrate 5 days, RNAseq
- GSM9211928 Tmprss2CreERT2, lsl-EYFP, whole prostate, Tamoxifen 2 weeks, castrate 5 days, Multiplexing
- GSM9211929 Tmprss2CreERT2, lsl-EYFP, whole prostate, Tamoxifen 2 weeks, castrate 2 weeks, DHT 2 days, RNAseq
- GSM9211930 Tmprss2CreERT2, lsl-EYFP, whole prostate, Tamoxifen 2 weeks, castrate 2 weeks, DHT 2 days, Multiplexing
- GSM9211931 Tmprss2CreERT2, lsl-EYFP, whole prostate, Tamoxifen 2 weeks, castrate 2 weeks, DHT 2 weeks, RNAseq
- GSM9211932 Tmprss2CreERT2, lsl-EYFP, whole prostate, Tamoxifen 2 weeks, castrate 2 weeks, DHT 2 weeks, Multiplexing
- GSM9211933 Tmprss2CreERT2, lsl-EYFP, Anterior prostate, Tamoxifen 4 weeks, scRNAseq, No Multiplexing
- GSM9211934 Tmprss2CreERT2, lsl-EYFP, Arf/Y, Anterior prostate, Tamoxifen 4 weeks, scRNAseq, No Multiplexing
- GSE306262 Astrocyte glucocorticoid receptor signaling restricts neuronal plasticity [RNA-seq] 40 samples shares plasticity, receptor
- GSE227108 Integrated single-cell analysis defines the epigenetic basis of castration-resistant prostate luminal cells (scRNA-seq) 18 samples shares scrna-seq, luminal
- GSE273440 A tumor-associated photoreceptor signature unifies distinct central nervous system malignancies [scRNA-seq] 13 samples shares scrna-seq, receptor
- GSE240036 Therapeutic potential of co-signaling receptor modulation in hepatitis B [scRNA-Seq] 10 samples shares scrna-seq, receptor
- GSE326641 Ubiquitin-like proteins NEDD8 and SUMO2 control epithelial homeostasis, regeneration, and inflammation [scRNA-seq] 8 samples shares regeneration, scrna-seq
- GSE306265 Astrocyte glucocorticoid receptor signaling restricts neuronal plasticity 106 samples shares plasticity, receptor
- GSE275296 H3K36 methylation regulates cell plasticity and regeneration in the intestinal epithelium [cutandtag_enzyme_profiling] 12 samples shares regeneration, plasticity
- GSE306261 Astrocyte glucocorticoid receptor signaling restricts neuronal plasticity [CUT&RUN] 50 samples shares plasticity, receptor
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.