← BioTransfer GEO Dataset Finder
GEO series

Transcriptome profiles of male wild-type and IRF8 knockout microglia

GSE307015 Mus musculus Expression profiling by high throughput sequencing 6 samples Submitted 2026/02/01 Platform GPL19057
Summary
The lineage-determining transcription factor IRF8's function in microglia, particularly concerning gender differences, is yet unclear. Our study aims to identify the gender biases in gene expression in WT and IRF8 knockout microglia. This mRNA transcrptome data provides a new understanding of the gender-associated transcriptional programs in microglia.
Published in
IRF8 deficiency causes anxiety-like behavior in a sex-dependent manner
Zhu S, Saeki K, Karlsson RM et al. · bioRxiv : the preprint server for biology 2025 · PMID 40950089 · doi:10.1101/2025.09.02.673764
This dataset
Download

Direct links to NCBI, no account and no request form: the whole study as GSE307015_RAW.tar, processed values as the series matrix, the supplementary file directory, and per-sample supplementary files for any of the 6 samples. Raw sequencing reads are also available from ENA.

Also filed as BioProject PRJNA1314111 and SRA study SRP616715. Searching any of these in the dataset finder brings you back here.

Samples in this study

The sample list for this study is not cached yet. Press Sort into groups and it will be fetched from NCBI.

+ 6 more — browse all 6 samples with per-sample file links →

Similar datasets

Search all mouse RNA-seq datasets in GEO →

Share this dataset

Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.