GEO series
Single cell RNAseq on rheumatoid arthritis-related interstitial lung disease
GSE307297
Homo sapiens
Expression profiling by high throughput sequencing
12 samples
2026/02/06
GPL34284
Summary
Rheumatoid arthritis (RA) is a chronic autoimmune disease characterized by synovitis and/or joint deterioration. Interstitial lung disease (ILD) is one of extra-articular manifestations of RA characterized by inflammation and/or fibrosis. Clinically relevant rheumatoid arthritis-related interstitial lung disease (RA-ILD) occurs in 10% of RA patients and is associated with poor prognosis. Although a poor prognosis has been reported, little is known about RA-ILD. Here, we report the first detailed transcriptomic analysis of the epithelial and immune cell populations in RA-ILD lungs at the single-cell level.
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Paper (PMID 41629202) ↗
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