Mapping the Dialogue: Decoding Alveolar Stem-Niche Interactions
RNA-seq (gene expression) · human · 890 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Homo sapiens (human)
- Samples
- 890 samples: 890 samples, each with a distinct title — no replicated groupsGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE307351_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1315700 and SRA study SRP616810. Searching any of these in the dataset finder brings you back here.
Any grouping that defines a comparison lives in the sample characteristics, which GEO records separately from the titles.
How we read this: Read from the first 400 of 890 sample titles: 400 distinct titles with little repetition. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM9215859 lung alveolar organoid, Met knockout, plate1-1 well B02
- GSM9215860 lung alveolar organoid, Glis3 knockout, plate1-1 well B03
- GSM9215861 lung alveolar organoid, Tigit knockout, plate1-1 well B04
- GSM9215862 lung alveolar organoid, Tdtomato knockout, plate1-1 well B05
- GSM9215863 lung alveolar organoid, Trp53 knockout, plate1-1 well B06
- GSM9215864 lung alveolar organoid, Acp6 knockout, plate1-1 well B07
- GSM9215865 lung alveolar organoid, Pink1 knockout, plate1-1 well B08
- GSM9215866 lung alveolar organoid, Eif2ak3 knockout, plate1-1 well B09
- GSM9215867 lung alveolar organoid, Ccbe1 knockout, plate1-1 well B10
- GSM9215868 lung alveolar organoid, Gdf2 knockout, plate1-1 well B11
- GSM9215869 lung alveolar organoid, Tead1 knockout, plate1-1 well C02
- GSM9215870 lung alveolar organoid, Mecom knockout, plate1-1 well C03
- GSM9215871 lung alveolar organoid, Huwe1 knockout, plate1-1 well C04
- GSM9215872 lung alveolar organoid, Sftpd knockout, plate1-1 well C05
- GSM9215873 lung alveolar organoid, Trp63 knockout, plate1-1 well C06
- GSM9215874 lung alveolar organoid, Il1a knockout, plate1-1 well C07
- GSM9215875 lung alveolar organoid, Prkn knockout, plate1-1 well C08
- GSM9215876 lung alveolar organoid, Tigit knockout, plate1-1 well C09
- GSM9215877 lung alveolar organoid, Bmp10 knockout, plate1-1 well C10
- GSM9215878 lung alveolar organoid, Pla2g15 knockout, plate1-1 well C11
- GSM9215879 lung alveolar organoid, Ror1 knockout, plate1-1 well D02
- GSM9215880 lung alveolar organoid, Npnt knockout, plate1-1 well D03
- GSM9215881 lung alveolar organoid, Rnf43 knockout, plate1-1 well D04
- GSM9215882 lung alveolar organoid, Tns1 knockout, plate1-1 well D05
- GSM9215883 lung alveolar organoid, Ttf1 knockout, plate1-1 well D06
- GSM9215884 lung alveolar organoid, Tigit knockout, plate1-1 well D07
- GSM9215885 lung alveolar organoid, Keap1 knockout, plate1-1 well D08
- GSM9215886 lung alveolar organoid, Tfeb knockout, plate1-1 well D09
- GSM9215887 lung alveolar organoid, Fgf7 knockout, plate1-1 well D10
- GSM9215888 lung alveolar organoid, Il1a knockout, plate1-1 well D11
- GSM9215889 lung alveolar organoid, Tfcp2l1 knockout, plate1-1 well E02
- GSM9215890 lung alveolar organoid, Tigit knockout, plate1-1 well E03
- GSM9215891 lung alveolar organoid, Sox4 knockout, plate1-1 well E04
- GSM9215892 lung alveolar organoid, Twist1 knockout, plate1-1 well E05
- GSM9215893 lung alveolar organoid, Nkx21 knockout, plate1-1 well E06
- GSM9215894 lung alveolar organoid, Usp30 knockout, plate1-1 well E07
- GSM9215895 lung alveolar organoid, Nfe2l2 knockout, plate1-1 well E08
- GSM9215896 lung alveolar organoid, Ulk1 knockout, plate1-1 well E09
- GSM9215897 lung alveolar organoid, Inhba knockout, plate1-1 well E10
- GSM9215898 lung alveolar organoid, Manf knockout, plate1-1 well E11
+ 850 more — browse all 890 samples with per-sample file links →
- GSE240326 An in situ method for identification of transcriptome-wide protein-RNA interactions in cells 78 samples shares interactions
- GSE243750 SEX-DEPENDENT APOE4 NEUTROPHIL-MICROGLIA INTERACTIONS DRIVE COGNITIVE IMPAIRMENT IN ALZHEIMER'S DISEASE 288 samples shares interactions
- GSE262989 Psychedelic control of neuroimmune interactions governing fear 108 samples shares interactions
- GSE296242 Sustained MYB activity drives emergent enhancer activation and precise enhancer-promoter interactions 81 samples shares interactions
- GSE246318 Decoding the immune checkpoint signatures in human atherosclerosis: implications of type 2 diabetes and lipid-lowering intervention 49 samples shares decoding
- GSE66383 Disruptions of Topological Chromatin Domains Causes Pathogenic Rewiring of Gene-Enhancer Interactions 31 samples shares interactions
- GSE203109 Single-molecule simultaneous profiling of DNA methylation and DNA-protein interactions with Nanopore-DamID 10 samples shares interactions
- GSE35156 Conserved Topological Domains in Mammalian Genomes Identified by High-resolution Analysis of Chromatin Interactions 9 samples shares interactions
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.