Protective effects of swimming exercises on murine tumor-induced cardiac inflammation and apoptosis by suppressing PI3K-AKT pathway
RNA-seq (gene expression) · mouse · 17 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Mus musculus (mouse)
- Samples
- 17 samples: 6 × M vs 6 × S vs 5 × CGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE308218_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1329245 and SRA study SRP620804. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 17 samples.
How we read this: 3 replicated groups read from 17 sample titles; they account for 17 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM9240352 C1 C
- GSM9240353 C2 C
- GSM9240354 C3 C
- GSM9240355 C4 C
- GSM9240356 C5 C
- GSM9240357 M1 M
- GSM9240358 M2 M
- GSM9240359 M3 M
- GSM9240360 M4 M
- GSM9240361 M5 M
- GSM9240362 M6 M
- GSM9240363 S1 S
- GSM9240364 S2 S
- GSM9240365 S3 S
- GSM9240366 S4 S
- GSM9240367 S5 S
- GSM9240368 S6 S
- GSE311091 Zeb2os Hinders Cardiac Healing by Suppressing ZEB2 Reactivation and Cardiomyocyte Dedifferentiation 20 samples shares suppressing, cardiac
- GSE311093 Zeb2os Hinders Cardiac Healing by Suppressing ZEB2 Reactivation and Cardiomyocyte Dedifferentiation [2] 13 samples shares suppressing, cardiac
- GSE271317 Deletion of Bmal1 in Intestinal Epithelium Protects against Colonic Inflammation by Suppressing the Apoptosis Pathway 12 samples shares suppressing, apoptosis
- GSE249554 The neuroprotective effect of TGF-β1 on mechanically injured cortical murine neurons by reducing trauma-induced autophagy and apoptosis 12 samples shares protective, apoptosis
- GSE288213 Altered pathways in Cockayne syndrome: Involvement of MAPK, PI3K-Akt, extracellular matrix, inflammation, and neuronal signaling 30 samples shares pi3k-akt
- GSE305628 Isobavachalcone ameliorates TNBS-induced Crohn’s disease-like colitis via GPR84-PI3K-AKT axis 18 samples shares pi3k-akt
- GSE315769 Sex and tissue resolved co-expression networks reveal a female placental–brain axis protective against prenatal PCB exposure 192 samples shares protective
- GSE269493 Hepatoprotective effects of late-stage clinical drug candidates and dietary intervention in the non-obese CDAA-HFD mouse model of advanced MASH with progressive fibrosis 81 samples shares protective
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.