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Mimicking opioid analgesia in cortical pain circuits

GSE308301 Mus musculus Expression profiling by high throughput sequencing 14 samples 2026/01/09 GPL24247
Summary
We performed single nuclei transcriptomics on the anterior cingulate cortex of mice cohorts that received either neuropathic pain (sciatic nerve injury) or sham surgery, followed by varying posto-injury periods (3 days, 3 weeks, or 3 months). Five minutes prior to tissue collection, pain active genes were stimulated via one second static fiber (0.16g) to each hind paw (1x/30sec/5min).
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NCBI GEO page ↗ Paper (PMID 41501467) ↗ {# Names what the click gives you. "Open in finder" meant nothing to a visitor who arrived from a search engine and has never seen the tool. #} Find more mouse RNA-seq datasets →
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