Single nucleus tanscriptomic analysis of the mouse enteric nervous system
Single-nucleus RNA-seq · mouse · 15 samples
- What it is
- Single-nucleus RNA-seqGene activity measured in individual nuclei (used when whole cells are hard to isolate, for example from frozen tissue). Read from the summary: GEO's own type field only says 'expression profiling by sequencing', so confirm it in the paper.
- Organism
- Mus musculus (mouse)
- Samples
- 15 samples: 15 × Mouse ENSGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- In vivo transcriptomic, functional, circuit-based, and translational analyses of enteric neuronsCell · 2025
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE308383_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: Single-cell studies usually ship their counts as 10x files (matrix.mtx, barcodes.tsv, features.tsv), an .h5 file, or an .rds / .h5ad object that Seurat or Scanpy can open. Look for those among the supplementary files.
Also filed as BioProject PRJNA1330319 and SRA study SRP621325. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 15 samples.
How we read this: 1 replicated groups read from 15 sample titles; they account for 15 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM9244343 Mouse ENS 39 Mouse ENS
- GSM9244344 Mouse ENS 40 Mouse ENS
- GSM9244345 Mouse ENS 41 Mouse ENS
- GSM9244346 Mouse ENS 42 Mouse ENS
- GSM9244347 Mouse ENS 44 Mouse ENS
- GSM9244348 Mouse ENS 46 Mouse ENS
- GSM9244349 Mouse ENS 47 Mouse ENS
- GSM9244350 Mouse ENS 49 Mouse ENS
- GSM9244351 Mouse ENS 57 Mouse ENS
- GSM9244352 Mouse ENS 58 Mouse ENS
- GSM9244353 Mouse ENS 59 Mouse ENS
- GSM9244354 Mouse ENS 60 Mouse ENS
- GSM9244355 Mouse ENS 61 Mouse ENS
- GSM9244356 Mouse ENS 62 Mouse ENS
- GSM9244357 Mouse ENS 63 Mouse ENS
- GSE302208 Regional encoding of enteric nervous system responses to microbiota and type 2 inflammation [Neuron SmartSeq2] 169 samples shares enteric, nervous, system
- GSE263945 Inflammation Rewires the Enteric Nervous System Through Neurogenic Monocyte Recruitment 33 samples shares enteric, nervous, system
- GSE275794 Tachykinin signaling defines distinct populations of glia in the enteric nervous system [Bulk RNA-seq] 19 samples shares enteric, nervous, system
- GSE301963 Regional encoding of enteric nervous system responses to microbiota and type 2 inflammation [10xGermfree] 16 samples shares enteric, nervous, system
- GSE302051 Regional encoding of enteric nervous system responses to microbiota and type 2 inflammation [10xPerturbSeq] 14 samples shares enteric, nervous, system
- GSE229916 Pericytes and perivascular fibroblasts contribute to central nervous system fibrosis in a region dependent manner 832 samples shares nervous, system
- GSE270197 Comparative Analysis of In vivo Endothelial Cell Translatomes Across Central Nervous System Vascular Beds (Tie2) 18 samples shares nervous, system
- GSE275306 A tumor-associated photoreceptor signature unifies distinct central nervous system malignancies [bulkRNA-seq] 39 samples shares nervous, system
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.