GEO series
CHD3 and CHD4 coordinate gene expression programs to maintain β-cell function and identity in vivo [RNA-seq]
GSE308564
Mus musculus
Expression profiling by high throughput sequencing
11 samples
2026/02/20
GPL24247
Summary
To establish the role of CHD3 and CHD4 on controlling gene expression programs in the beta cell, we generated a tamoxifen-inducible, beta-cell-specific knockout mouse models; control (MIP-CreERT; Chd3+/+; Chd4+/+; R26RtdTomato), Chd3Db (MIP-CreERT; Chd3f/f; Chd4+/+; R26RtdTomato) and Chd3/4Db (MIP-CreERT; Chd3f/f; Chd4f/f; R26RtdTomato)
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Paper (PMID 41282155) ↗
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