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Gcm1 ChIP-seq of C57BL/6 mouse embryonic stem cells with folate deficiency

GSE308655 Mus musculus Genome binding/occupancy profiling by high throughput sequencing 4 samples Submitted 2025/12/04 Platform GPL24247
Summary
In order to investigate whether folate deficiency affects Gcm1 enrichment and then affecting the activity of Wnt signaling pathway, we performed ChIP-seq of Gcm1 on folate-free embryonic stem cells and normal embryonic stem cells, respectively. Our sequencing data provides a new theoretical basis for the effect of folate on histone modification.
Published in
Gcm1 Orchestrates Lef1 Expression in Folate Deficiency-Induced Neural Tube Defects
Cao Z, Li L, Gu X et al. · Molecular neurobiology 2025 · PMID 41217685 · doi:10.1007/s12035-025-05346-x
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Also filed as BioProject PRJNA1331816 and SRA study SRP622709. Searching any of these in the dataset finder brings you back here.

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