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Proteolytic disruption of renal endothelial glycocalyx in sepsis: Dexamethasone inhibition via TLR4/NF-κB/MMP axis

GSE309047 Mus musculus Expression profiling by high throughput sequencing 6 samples Submitted 2025/10/01 Platform GPL17021
Summary
Investigate the differences in gene expression in the kidneys of mice with sepsis, and by comparing with the sham operation group, analyze the differentially expressed genes and signaling pathways.
Published in
Targeting the TLR4/NF-κB/TNF-α/MMP axis with dexamethasone attenuates glycocalyx degradation and restores microcirculatory perfusion in septic kidneys
Fu M, Zhao J, Xu W et al. · Scientific reports 2026 · PMID 42014490 · doi:10.1038/s41598-026-49713-7
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Also filed as BioProject PRJNA1333855 and SRA study SRP626382. Searching any of these in the dataset finder brings you back here.

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