Step-wise signal integration governs adaptive programming of lymphocytes [bulkRNA-seq and ATAC-seq 6hr Stim]
ChIP-seq / ATAC-seq (genome binding and open chromatin) · mouse · 16 samples
- What it is
- ChIP-seq / ATAC-seq (genome binding and open chromatin)Where proteins bind the genome, or which regions are open and active.
- Organism
- Mus musculus (mouse)
- Samples
- 16 samples: 16 samples, each with a distinct title — no replicated groupsGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- Stepwise epigenetic signal integration drives adaptive programming of cytotoxic lymphocytesImmunity · 2026
Read the full summary ↓
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE309245_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: Look for peak files (.bed, .narrowPeak) and signal tracks (.bigWig) among the supplementary files; the raw reads are on ENA.
Also filed as BioProject PRJNA1334403 and SRA study SRP627335. Searching any of these in the dataset finder brings you back here.
Any grouping that defines a comparison lives in the sample characteristics, which GEO records separately from the titles.
How we read this: Read from 16 sample titles: 16 distinct titles with little repetition. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM9263573 RNA_TotalNK_Ly49H_6hr_1_IGO_12001_21
- GSM9263574 RNA_TotalNK_Ly49H_6hr_2_IGO_12001_22
- GSM9263575 RNA_TotalNK_Ly49H_6hr_3_IGO_12001_23
- GSM9263576 RNA_TotalNK_NK11_6hr_1_IGO_12001_17
- GSM9263577 RNA_TotalNK_NK11_6hr_2_IGO_12001_18
- GSM9263578 RNA_TotalNK_NK11_6hr_3_IGO_12001_19
- GSM9263579 RNA_TotalNK_Unstim_6hr_1_IGO_12001_13
- GSM9263580 RNA_TotalNK_Unstim_6hr_2_IGO_12001_14
- GSM9263581 ATAC_TotalNK_Ly49H_6hr_1_IGO_12002_B_15
- GSM9263582 ATAC_TotalNK_Ly49H_6hr_2_IGO_12002_B_16
- GSM9263583 ATAC_TotalNK_Ly49H_6hr_4_IGO_12002_B_18
- GSM9263584 ATAC_TotalNK_NK11_6hr_1_IGO_12002_B_19
- GSM9263585 ATAC_TotalNK_NK11_6hr_2_IGO_12002_B_20
- GSM9263586 ATAC_TotalNK_NK11_6hr_3_IGO_12002_B_21
- GSM9263587 ATAC_TotalNK_Unstim_6hr_1_IGO_12002_B_11
- GSM9263588 ATAC_TotalNK_Unstim_6hr_2_IGO_12002_B_12
- GSE292377 Step-wise signal integration governs adaptive programming of lymphocytes [bulkRNA-seq and ATAC-seq] 41 samples shares integration, programming, lymphocytes, bulkrna-seq, step-wise, adaptive, atac-seq, governs
- GSE302858 Multi-tier signaling and epigenomic reprogramming drive microglial inflammatory states and functions associated with demyelination [ATAC-seq] 42 samples shares programming, atac-seq
- GSE304037 Decoupling oxidative resilience from reprogramming to rejuvenate the RPE and restore vision [GSTA4_ATAC-seq_1] 42 samples shares programming, atac-seq
- GSE286574 Intrauterine hyperglycemia impairs primordial germ cell development and fertility by sex-specific epigenetic reprogramming interference in mice offspring [ATAC-seq] 30 samples shares programming, atac-seq
- GSE267447 Loss of Nuclear Receptor Nr4a3 Alleviates Cellular Senescence to Promote Adult Direct Cardiac Reprogramming (ATAC-Seq) 16 samples shares programming, atac-seq
- GSE283662 Multiscale integration of tissue and chromatin context converts cell heterogeneity into stable intestinal patterning 22 samples shares integration
- GSE268822 Transcriptional landscapes underlying Notch-induced lineage conversion and reprogramming of mammary cells 840 samples shares programming
- GSE319319 Xist RNA Dependent and Independent Mechanisms Regulate Dynamic X Chromosome Inactivation in B Lymphocytes 202 samples shares lymphocytes
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.