Nucleophosmin supports WNT-driven hyperproliferation and tumour initiation
RNA-seq (gene expression) · mouse · 111 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Mus musculus (mouse)
- Samples
- 111 samples: 20 conditions, mostly with about 4 replicates eachGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- Nucleophosmin supports WNT-driven hyperproliferation and tumor initiationNature genetics · 2026
Read the full summary ↓
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE309379_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1335271 and SRA study SRP628595. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 111 samples.
How we read this: 20 replicated groups read from 111 sample titles; they account for 111 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM9266501 AhApc SI Rep1 AhApc SI
- GSM9266502 AhApc SI Rep2 AhApc SI
- GSM9266503 AhApc SI Rep3 AhApc SI
- GSM9266504 AhApc SI Rep4 AhApc SI
- GSM9266505 AhApc SI Rep5 AhApc SI
- GSM9266506 AhApc SI Rep6 AhApc SI
- GSM9266507 AhApcMyc SI Rep1 AhApcMyc SI
- GSM9266508 AhApcMyc SI Rep2 AhApcMyc SI
- GSM9266509 AhApcMyc SI Rep3 AhApcMyc SI
- GSM9266510 AhApcMyc SI Rep4 AhApcMyc SI
- GSM9266511 VilCre Colon Rep1 VilCre Colon
- GSM9266512 VilCre Colon Rep2 VilCre Colon
- GSM9266513 VilCre Colon Rep3 VilCre Colon
- GSM9266514 VilCre Colon Rep4 VilCre Colon
- GSM9266515 VilCre SI Rep1 VilCre SI
- GSM9266516 VilCre SI Rep2 VilCre SI
- GSM9266517 VilCre SI Rep3 VilCre SI
- GSM9266518 VilCre SI Rep4 VilCre SI
- GSM9266519 VilApc Colon Rep1 VilApc Colon
- GSM9266520 VilApc Colon Rep2 VilApc Colon
- GSM9266521 VilApc Colon Rep3 VilApc Colon
- GSM9266522 VilApc Colon Rep4 VilApc Colon
- GSM9266523 VilApc Colon Rep5 VilApc Colon
- GSM9266524 VilApc Colon Rep6 VilApc Colon
- GSM9266525 VilApc Colon Rep7 VilApc Colon
- GSM9266526 VilApc Colon Rep8 VilApc Colon
- GSM9266527 VilApc Colon Rep9 VilApc Colon
- GSM9266528 VilApc Colon Rep10 VilApc Colon
- GSM9266529 VilApc Colon Rep11 VilApc Colon
- GSM9266530 VilApc Colon Rep12 VilApc Colon
- GSM9266531 VilApc SI Rep1 VilApc SI
- GSM9266532 VilApc SI Rep2 VilApc SI
- GSM9266533 VilApc SI Rep3 VilApc SI
- GSM9266534 VilApc SI Rep4 VilApc SI
- GSM9266535 VilApc SI Rep5 VilApc SI
- GSM9266536 VilApc SI Rep6 VilApc SI
- GSM9266537 VilApc SI Rep7 VilApc SI
- GSM9266538 VilApc SI Rep8 VilApc SI
- GSM9266539 VilApc SI Rep9 VilApc SI
- GSM9266540 VilApc SI Rep10 VilApc SI
+ 71 more — browse all 111 samples with per-sample file links →
- GSE241380 Crypt density and recruited enhancers underlie intestinal tumour initiation 13 samples shares initiation
- GSE314202 Loss of rhomboid protease RHBDL4 delays tumour initiation in a mouse model of breast cancer 10 samples shares initiation
- GSE255212 Transcriptomic Signatures of WNT-Driven Pathways and Granulosa Cell-Oocyte Interaction during Primordial Follicle Activation 762 samples shares wnt-driven
- GSE286046 Asymmetric Histone Inheritance Regulates Differential Transcription Re-initiation and Cell Fate Decisions in Mouse Olfactory Horizontal Basal Cells 96 samples shares initiation
- GSE294512 eIF4G2-mediated Translation Initiation of Histone Modifiers is Essential for Intestinal Stem Cell Maintenance and Differentiation [RNA-seq] 92 samples shares initiation
- GSE92966 The role of Lgr5 intestinal cancer stem cells in tumour initiation, progression and metastasis 48 samples shares initiation
- GSE241384 Crypt density and recruited enhancers underlie intestinal tumour initiation 46 samples shares initiation
- GSE241382 Crypt density and recruited enhancers underlie intestinal tumour initiation [ATAC-seq] 32 samples shares initiation
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.