Acute kidney injury following fatty liver ischemia-reperfusion injury: indirect protection by hepatic ferroptosis inhibition
RNA-seq (gene expression) · mouse · 12 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Mus musculus (mouse)
- Samples
- 12 samples: 3 × Kidney_ND-SHAM vs 3 × Kidney_ND-IRI vs 3 × Kidney_HFD-SHAM vs 3 × Kidney_HFD-IRIGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- Acute kidney injury following fatty liver ischemia-reperfusion injury: indirect protection by hepatic ferroptosis inhibitionFrontiers in physiology · 2025
Read the full summary ↓
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE309904_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1363975 and SRA study SRP644505. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 12 samples.
How we read this: 4 replicated groups read from 12 sample titles; they account for 12 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM9284669 Kidney_ND-SHAM_1 Kidney_ND-SHAM
- GSM9284670 Kidney_ND-SHAM_2 Kidney_ND-SHAM
- GSM9284671 Kidney_ND-SHAM_3 Kidney_ND-SHAM
- GSM9284672 Kidney_ND-IRI_1 Kidney_ND-IRI
- GSM9284673 Kidney_ND-IRI_2 Kidney_ND-IRI
- GSM9284674 Kidney_ND-IRI_3 Kidney_ND-IRI
- GSM9284675 Kidney_HFD-SHAM_1 Kidney_HFD-SHAM
- GSM9284676 Kidney_HFD-SHAM_2 Kidney_HFD-SHAM
- GSM9284677 Kidney_HFD-SHAM_3 Kidney_HFD-SHAM
- GSM9284678 Kidney_HFD-IRI_1 Kidney_HFD-IRI
- GSM9284679 Kidney_HFD-IRI_2 Kidney_HFD-IRI
- GSM9284680 Kidney_HFD-IRI_3 Kidney_HFD-IRI
- GSE295974 Single-cell multi-omics reveal coordinated neoplastic and immune remodeling following KRAS inhibition 64 samples shares inhibition, following
- GSE267650 Mouse kidney ischemia-reperfusion injury time course 57 samples shares ischemia-reperfusion, kidney
- GSE322775 Coordinated immune activation following KRAS inhibition reveals molecular pathways that potentiate and limit anti-tumor immunity 47 samples shares inhibition, following
- GSE306012 Temporal inhibition of ADAM17 in fibroblasts reduces stiffness and promotes vascularization following myocardial infarction 28 samples shares inhibition, following
- GSE272274 Effects of hepatic mARC1 inhibition in a mouse model of liver fibrosis 25 samples shares inhibition, hepatic
- GSE289792 Inhibition of microglial SLC2A5 attenuates brain injury following acute ischemic stroke [RNA-Seq] 12 samples shares inhibition, following
- GSE274819 Single-cell RNA sequencing of murine kidneys for ischemia-reperfusion induced renal injury and fibrosis 10 samples shares ischemia-reperfusion, kidney
- GSE318028 Pharmacological inhibition of FKBP51 mitigates early life adversity-induced social deficits 246 samples shares inhibition
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.