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Nutrigenomic profiling identifies ZIP10 (SLC39A10) as a regulator of erythroid zinc homeostasis with genetic associations to anemia risk II

GSE310207 Mus musculus Expression profiling by high throughput sequencing 7 samples Submitted 2025/11/19 Platform GPL24247
Summary
To determine the physiological roles of zinc in erythroid progenitor cells, cellular zinc was restricted by 50 µM DTPA treatment (a zinc chelator) for 24 hours in differentiating G1E-ER4 cells. G1E-ER4 cells induced for differentiation by beta-estradiol were divided into two groups: control and 50 µM DTPA treatment. A sample from cells untreated with beta-estradiol was also included as an undifferentiated group.
Published in
Nutrigenomic profiling identifies ZIP10 (SLC39A10) as a regulator of erythroid zinc homeostasis with genetic associations to anemia risk
Kim J, Sun Y, Ye K et al. · Proceedings of the National Academy of Sciences of the United States of America 2026 · PMID 41701827 · doi:10.1073/pnas.2533600123
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Also filed as BioProject PRJNA1365274 and SRA study SRP645554. Searching any of these in the dataset finder brings you back here.

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