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Improved co-transcriptional splicing of readthrough transcripts during chemotherapy treatment [CML_RNA-seq]

GSE310243 Homo sapiens Expression profiling by high throughput sequencing 8 samples Submitted 2026/02/15 Platform GPL24676
Summary
The cellular stress response is an important component of cancer cell response to chemotherapy that can determine cell survival. Herein, we study how the coupling of the RNA processes in leukemia cells is affected in response to stress and therapeutic agents. We used short- and long-read sequencing to follow RNA processing upon treatment.
Published in
Transcriptional readthrough precedes alternative splicing programs triggered in CML cells by imatinib
Podszywałow-Bartnicka P, Shine M, Lin J et al. · bioRxiv : the preprint server for biology 2025 · PMID 41279586 · doi:10.1101/2025.11.04.686193
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Also filed as BioProject PRJNA1365523 and SRA study SRP645787. Searching any of these in the dataset finder brings you back here.

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