RNA sequencing for gastric-type endocervical adenocarcinoma (GAS), usual-type endocervical adenocarcinoma (UEA), and lobular endocervical glandular hyperplasia (LEGH)
RNA-seq (gene expression) · human · 18 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Homo sapiens (human)
- Topic
- Cervical cancerThis series is part of our curated briefing on it.
- Samples
- 18 samples: 8 × LEGH vs 5 × GAS vs 5 × UEAGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- Transcriptome profiling identifies RET activation as a therapeutic target in gastric-type endocervical adenocarcinomaBiomedicine & pharmacotherapy = Biomedecine & pharmacotherapie · 2026
Read the full summary ↓
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE311549_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1369845 and SRA study SRP649118. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 18 samples.
How we read this: 3 replicated groups read from 18 sample titles; they account for 18 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM9326879 GAS1 GAS
- GSM9326880 GAS3 GAS
- GSM9326881 GAS4 GAS
- GSM9326882 GAS6 GAS
- GSM9326883 GAS7 GAS
- GSM9326884 UEA1 UEA
- GSM9326885 UEA3 UEA
- GSM9326886 UEA4 UEA
- GSM9326887 UEA6 UEA
- GSM9326888 UEA7 UEA
- GSM9326889 LEGH1 LEGH
- GSM9326890 LEGH2 LEGH
- GSM9326891 LEGH3 LEGH
- GSM9326892 LEGH5 LEGH
- GSM9326893 LEGH6 LEGH
- GSM9326894 LEGH7 LEGH
- GSM9326895 LEGH8 LEGH
- GSM9326896 LEGH9 LEGH
- GSE316098 Spatial Transcriptomic Landscape of Invasion Patterns in Human Papillomavirus-Associated Endocervical Adenocarcinoma 186 samples same disease briefing · shares adenocarcinoma, endocervical
- GSE264492 Transcriptomic analysis reveals Streptococcus agalactiae activation of oncogenic pathways in cervical adenocarcinoma 24 samples same disease briefing · shares adenocarcinoma
- GSE303300 Neoadjuvant Immune Checkpoint Blockade Before Chemoradiation for Patients with FIGO Stage IB3–IVA Cervical Squamous Carcinoma: GINECO Window-Of-Opportunity COLIBRI Study 96 samples same disease briefing
- GSE168244 Patient-derived organoids as a platform to study cervical cancer and viral infection 36 samples same disease briefing
- GSE299125 Paracrine Signals from HIV-1 Infected Immune Cells Reprogram Cervical Cancer Pathways 35 samples same disease briefing
- GSE297038 Chemoradiation Reprograms Tumor Cells and Immune Microenvironment In Cervical Cancer [bulk RNA-seq] 34 samples same disease briefing
- GSE275914 RNA sequencing of 31 pre-treatment, primary cervical cancer samples 31 samples same disease briefing
- GSE311189 Integrated Transcriptomic and Functional Analysis Reveals Selective Cytotoxicity and Oncogene Suppression Induced by Cinnamon Essential Oil in Cervical Cancer Cells 24 samples same disease briefing
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.