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NRF2 upregulation by CDDO-Me protects AC16 human cardiomyocytes against doxorubicin-induced toxicity_1.

GSE313504 Homo sapiens Expression profiling by high throughput sequencing 6 samples Submitted 2025/12/12 Platform GPL24676
Summary
Elucidation of the mechanisms underpinning doxorubicin-induced toxicity in human AC16 cells and the protection afforded by the NRF2 inducer CDDO-Me.
Published in
NRF2 upregulation by CDDO-Me protects AC16 human cardiomyocytes against doxorubicin-induced toxicity
Roberts JA, Batie M, Ponsford AH et al. · Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2026 · PMID 41418664 · doi:10.1016/j.biopha.2025.118878
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Also filed as BioProject PRJNA1379664 and SRA study SRP654597. Searching any of these in the dataset finder brings you back here.

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