GEO series
Comprehensive transcriptome analysis of the Mettl18-deficient embryos
GSE314501
Mus musculus
Expression profiling by high throughput sequencing
10 samples
2026/01/23
GPL19057
Summary
Histidine methylation is an evolutionarily conserved but poorly understood post-translational modification. METTL18 is known to catalyze histidine Nτ-methylation in vitro, yet its physiological functions in mammals remain unclear. In this study, we performed a comprehensive analysis of gene expression changes in embryos of wild-type and Mettl18-deficient mice using RNA sequencing (RNA-seq).
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