GEO series
Differentially expressed genes in human monocyte-derived macrophages overexpressing TRIM21, NFATc3, or ASK1
GSE315074
Homo sapiens
Expression profiling by high throughput sequencing
12 samples
2026/01/26
GPL11154
Summary
We hypothesize that the TRIM21-NFATc3/ASK1 axis plays a key role in steatohepatitis. TRIM21, NFATc3, and ASK1 plasmids were transfected separately in human monocyte-derived macrophages(HMDMs), with the pCMV6 expression vector used as a control. Subsequently, RNA sequencing analysis was performed to obtain common feature genes for Connectivity Map screening.
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