Total RNA-seq of C2C12 myotubes treated with agrin or MuSK antibodies
RNA-seq (gene expression) · mouse · 20 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Mus musculus (mouse)
- Samples
- 20 samples: 5 conditions, mostly with about 4 replicates eachGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- MuSK antibodies differently affect the MuSK signaling cascade depending on valency and epitope specificityJournal of autoimmunity · 2026
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE316686_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1403584 and SRA study SRP662874. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 20 samples.
How we read this: 5 replicated groups read from 20 sample titles; they account for 20 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM9458235 b12 rep1 b12
- GSM9458236 13-3B5 rep1 13-3B5
- GSM9458237 Agrin b12 rep1 Agrin b12
- GSM9458238 Agrin 13-3B5xb12 rep1 Agrin 13-3B5xb12
- GSM9458239 Agrin 11-3F6xb12 rep1 Agrin 11-3F6xb12
- GSM9458240 b12 rep2 b12
- GSM9458241 13-3B5 rep2 13-3B5
- GSM9458242 Agrin b12 rep2 Agrin b12
- GSM9458243 Agrin 13-3B5xb12 rep2 Agrin 13-3B5xb12
- GSM9458244 Agrin 11-3F6xb12 rep2 Agrin 11-3F6xb12
- GSM9458245 b12 rep3 b12
- GSM9458246 13-3B5 rep3 13-3B5
- GSM9458247 Agrin b12 rep3 Agrin b12
- GSM9458248 Agrin 13-3B5xb12 rep3 Agrin 13-3B5xb12
- GSM9458249 Agrin 11-3F6xb12 rep3 Agrin 11-3F6xb12
- GSM9458250 b12 rep4 b12
- GSM9458251 13-3B5 rep4 13-3B5
- GSM9458252 Agrin b12 rep4 Agrin b12
- GSM9458253 Agrin 13-3B5xb12 rep4 Agrin 13-3B5xb12
- GSM9458254 Agrin 11-3F6xb12 rep4 Agrin 11-3F6xb12
- GSE283700 RNA-sequencing of SVF-derived preadipocytes from inguinal adipose tissue of male mice differentiating under control conditions or treated with CGRP 15 samples shares rna-seq, treated
- GSE264105 Plate-based scRNA-seq of plasma-positive microglia and plasma-negative microglia in young mice 1111 samples shares rna-seq
- GSE326100 scRNA-seq of mouse cochlea organoid cells 768 samples shares rna-seq
- GSE311449 Single cell RNA-seq of mouse brain vascular cells with Smart-seq2 method 391 samples shares rna-seq
- GSE319614 Bulk RNA-seq transcriptome profiling of hippocampus across 17 autism spectrum disorder mouse models 269 samples shares rna-seq
- GSE326452 Bulk RNA-seq of mouse brain following closed head injury: role of IL-1R1 signaling 200 samples shares rna-seq
- GSE98969 Single cell RNA-seq identifies a unique microglia type associated with Alzheimer’s disease [RNA] 97 samples shares rna-seq
- GSE342349 CT26 multi-tissue RNA-seq under immunotherapy combinations 72 samples shares rna-seq
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.