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Critical role of keratinocytes and PAR2 in secondary lymphedema development

GSE316723 Homo sapiens Expression profiling by high throughput sequencing 6 samples Submitted 2026/06/11 Platform GPL24676
Summary
Activated keratinocytes play a key role in the pathophysiology of secondary lymphedema through PAR2 by producing Th2-inducing cytokines that modulate skin inflammatory responses.
Published in
Critical role of keratinocytes and protease-activated receptor 2 in secondary lymphedema development
Park HJ, Pal S, Chen X et al. · Clinical and translational medicine 2026 · PMID 42226615 · doi:10.1002/ctm2.70682
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Also filed as BioProject PRJNA1403833 and SRA study SRP663455. Searching any of these in the dataset finder brings you back here.

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