Mild SARS-CoV-2 maternal infection in mice induces transient offspring neurodevelopmental aberrance
RNA-seq (gene expression) · mouse · 140 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Mus musculus (mouse)
- Samples
- 140 samples
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
Read the full summary ↓
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE317803_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1415288 and SRA study SRP668090. Searching any of these in the dataset finder brings you back here.
The sample list for this study is not cached yet. Press Load samples and it will be fetched from NCBI.
+ 140 more — browse all 140 samples with per-sample file links →
- GSE288224 Transient Pharmacological Inhibition of SUMOylation during Pregnancy Induces Craniofacial Malformations in Offspring Mice 18 samples shares transient, offspring, induces
- GSE270802 Diabetes induces exacerbated SARS-CoV-2 replication partly associated with ineffective pulmonary interferon responses, delayed cell-mediated immunity, and disruption of leptin receptor signaling 24 samples shares sars-cov-2, induces
- GSE300910 Respiratory syncytial virus infection induces heterologous protection against SARS-CoV-2 via induction of trained immunity and SARS-CoV-2 reactive mucosal T cells 15 samples shares sars-cov-2, induces
- GSE236201 Maternal Circadian Rhythms during Pregnancy Dictate Metabolic Plasticity in Offspring 96 samples shares offspring, maternal
- GSE280285 In Vitro Fertilization induces reproductive changes in male mouse offspring and has multigenerational effects [RNA-Seq] 72 samples shares offspring, induces
- GSE248222 Impact of Maternal Immune Activation and Sex on Placental and Fetal Brain Cytokine and Gene Expression Profiles in a Preclinical Model of Neurodevelopmental Disorders 64 samples shares neurodevelopmental, maternal
- GSE247323 Maternal indole supplementation protects offspring from NAFLD through altered microbiota- and AHR-mediated ceramide metabolism 40 samples shares offspring, maternal
- GSE256518 Partial beta cell loss induces transient compensatory proliferation II 34 samples shares transient, induces
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.