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Ribo-seq analysis analysis of SNU-668 Erastin-resistant cells transfected with shRNA-ALKBH3 or control shRNA

GSE317885 Homo sapiens Other; Expression profiling by high throughput sequencing 4 samples Submitted 2026/02/02 Platform GPL24676
Summary
This study presents a comprehensive ribosome profiling (Ribo-seq) analysis conducted on SNU-668 gastric cancer cells with acquired resistance to Erastin. These cells were genetically modified through stable transfection with either a short hairpin RNA (shRNA) construct specifically targeting and knocking down the expression of the ALKBH3 gene, or a corresponding non-targeting control shRNA, to systematically investigate the consequent alterations in global translational activity.
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Direct links to NCBI, no account and no request form: the whole study as GSE317885_RAW.tar, processed values as the series matrix, the supplementary file directory, and per-sample supplementary files for any of the 4 samples. Raw sequencing reads are also available from ENA.

Also filed as BioProject PRJNA1415752 and SRA study SRP668975. Searching any of these in the dataset finder brings you back here.

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