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Bone marrow RNA sequencing profiles from AML patients and healthy donors

GSE317967 Homo sapiens Expression profiling by high throughput sequencing 8 samples Submitted 2026/03/01 Platform GPL24676
Summary
Acute Myeloid Leukemia (AML) is a complex hematological malignancy characterized by the clonal expansion of undifferentiated myeloid precursors. Despite advances in treatment, intra-tumoral heterogeneity and the remodeling of the bone marrow (BM) microenvironment remain significant hurdles to durable remission. This study aims to characterize the distinct cellular landscapes of AML compared to healthy hematopoiesis to identify key drivers of leukemogenesis and immune evasion.
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Direct links to NCBI, no account and no request form: the whole study as GSE317967_RAW.tar, processed values as the series matrix, the supplementary file directory, and per-sample supplementary files for any of the 8 samples. Raw sequencing reads are also available from ENA.

Also filed as BioProject PRJNA1414824 and SRA study SRP667429. Searching any of these in the dataset finder brings you back here.

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