Transcriptomic profiling of neonatal mouse ventricular myocytes (NMVMs) under hypoxia and recombinant Serglycin stimulation
RNA-seq (gene expression) · mouse · 9 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Mus musculus (mouse)
- Samples
- 9 samples: 3 × Con vs 3 × Hypoxia vs 3 × Hypoxia+rSRGNGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- Identification and analysis of diagnostic senescence-related gene signatures for acute myocardial infarction based on multi-omics data and machine learningFrontiers in immunology · 2026
Read the full summary ↓
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE318951_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1420871 and SRA study SRP675881. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 9 samples.
How we read this: 3 replicated groups read from 9 sample titles; they account for 9 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM9506797 Con1 Con
- GSM9506798 Con2 Con
- GSM9506799 Con3 Con
- GSM9506800 Hypoxia1 Hypoxia
- GSM9506801 Hypoxia2 Hypoxia
- GSM9506802 Hypoxia3 Hypoxia
- GSM9506803 Hypoxia+rSRGN 1 Hypoxia+rSRGN
- GSM9506804 Hypoxia+rSRGN 2 Hypoxia+rSRGN
- GSM9506805 Hypoxia+rSRGN 3 Hypoxia+rSRGN
- GSE312675 Pressure Overload-Induced Ventricular Crosstalk Activates Regenerative Mechanisms in the Contralateral Ventricle in Neonatal Mice [RNA-Seq] 22 samples shares ventricular, neonatal
- GSE282365 Whole genome transcriptomics reveal distinct atrial versus ventricular responses to neonatal hyperoxia 20 samples shares ventricular, neonatal
- GSE309574 Transcriptional profiling defines unique subtypes of transit amplifying neural progenitors within the neonatal mouse subventricular zone 20 samples shares ventricular, neonatal
- GSE230859 Gene expression profile of adult ventricular myocytes (AVM) from mouse model B3AR-Tg and WT littermates 9 weeks post TAC surgery 16 samples shares ventricular, myocytes
- GSE277680 Mitochondrial Ferritin Inhibition Aggravates Pacing-induced Ventricular Arrhythmias after Myocardial Infarction by Promoting Cardiomyocytes Ferroptosis 12 samples shares ventricular, myocytes
- GSE262107 Next Generation Sequencing to identify the differential expression genes of murine lung tissues upon the stimulation of LPS with/without recombinant TSLP pretreatment 10 samples shares recombinant, stimulation
- GSE255004 Sensory Flicker Stimulation of 5xFAD Mice Activates Immune Pathways in a Frequency and Time Dependent Manner 176 samples shares stimulation
- GSE303256 A spatial and projection-based transcriptomic atlas of paraventricular hypothalamic cell types 131 samples shares ventricular
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.