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Efficacy Studies of Exosomal Formulations of Celastrol against A549 Lung Cancer Cells

GSE318992 Homo sapiens Expression profiling by high throughput sequencing 6 samples Submitted 2026/04/22 Platform GPL34284
Summary
In this study, the primary focus was to test the applicability of celastrol (CEL) against lung cancer using in vitro and in vivo models and to test wether loading CEL onto exosomes (Exo) help improve the cell uptake, tumor targetability, and bioavailability of CEL.
Published in
Tumor-targeted Exosomal Delivery of Celastrol for Enhanced Therapeutic Efficacy in NSCLC
Moholkar DN, Kandimalla R, Saeed M et al. · Theranostics 2026 · PMID 41993621 · doi:10.7150/thno.125096
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Also filed as BioProject PRJNA1420935 and SRA study SRP675941. Searching any of these in the dataset finder brings you back here.

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